Gene Symbol | SLC39A5 |
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Entrez Gene | 283375 |
Alt Symbol | LZT-Hs7, MYP24, ZIP5 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 39 (zinc transporter), member 5 |
Other Description | solute carrier family 39 (metal ion transporter), member 5|solute carrier family 39 member 5|zinc transporter ZIP5|zrt- and Irt-like protein 5 |
Swissprots | B2R808 Q6ZMH5 Q8N6Y3 |
Accessions | EAW96916 EAW96917 EAW96918 Q6ZMH5 AK172768 BAD18751 AK298331 BAG60580 AK313188 BAG36005 BC027884 AAH27884 DA640935 DA918133 XM_005268803 XP_005268860 XM_011538198 XP_011536500 XM_011538199 XP_011536501 XM_011538200 XP_011536502 XM_011538201 XP_011536503 XM_011538202 XP_011536504 XR_944520 NM_001135195 NP_001128667 NM_173596 NP_775867 |
Function | May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera (PubMed:24891338). Seems to play a central role in controlling organismal zinc status (By similarity). {ECO:0000250|UniProtKB:Q9D856, ECO:0000269|PubMed:24891338}. |
Subcellular Location | Basolateral cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney. {ECO:0000269|PubMed:15322118}. |
Human SLC39A5 full length protein - ab166129 from Abcam
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SLC39A5 / ZIP5 Antibody Blocking Peptide - LS-E16222 from LifeSpan Bioscience
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SLC39A5 / ZIP5 Antibody Blocking Peptide - LS-E16223 from LifeSpan Bioscience
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SLC39A5 / ZIP5 Antibody Blocking Peptide - LS-E31042 from LifeSpan Bioscience
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Recombinant Human SLC39A5 Protein - H00283375-P01 from Novus Biologicals
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SLC39A5 Peptide - NBP1-76502PEP from Novus Biologicals
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SLC39A5-Antibody-Center-Blocking-Peptide - BP17503c from Abgent, a WuXi AppTec company
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ZIP5 Peptide - GTX85132-PEP from GeneTex
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SLC39A5 Protein Lysate (APL10225) - APL10225 from Aviva Systems Biology
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SLC39A5 Protein Lysate (APL10481) - APL10481 from Aviva Systems Biology
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SLC39A5 Protein Lysate (APL10482) - APL10482 from Aviva Systems Biology
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SLC39A5 Protein Lysate (APL10483) - APL10483 from Aviva Systems Biology
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SLC39A5 Blocking Peptide - 33R-3877 from Fitzgerald
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SLC39A5 Blocking Peptide - 33R-6078 from Fitzgerald
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Zinc transporter ZIP5 / SLC39A5 - H00283375-P01-10 from Acris Antibodies
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Zinc transporter ZIP5 / SLC39A5 - H00283375-P01-25 from Acris Antibodies
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Zinc transporter ZIP5 / SLC39A5 control peptide - AP26310CP-N from Acris Antibodies
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ZIP5 Peptide - 6089P from ProSci
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SLC39A5 fusion protein - Ag11100 from Proteintech Group
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SLC39A5 fusion protein - Ag11067 from Proteintech Group
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Recombinant Human SLC39A5, His-tagged - SLC39A5-2765H from Creative Biomart
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Zinc transporter ZIP5 / SLC39A5 (transcript variant 1) - TP306665 from Acris Antibodies
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SLC39A5 Protein - NBP1-86044PEP from Novus Biologicals
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SLC39A5 Protein Lysate - orb333393 from Biorbyt
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SLC39A5 Protein Lysate - orb333195 from Biorbyt
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