Gene Symbol | SLC39A5 |
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Entrez Gene | 283375 |
Alt Symbol | LZT-Hs7, MYP24, ZIP5 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 39 (zinc transporter), member 5 |
Other Description | solute carrier family 39 (metal ion transporter), member 5|solute carrier family 39 member 5|zinc transporter ZIP5|zrt- and Irt-like protein 5 |
Swissprots | B2R808 Q6ZMH5 Q8N6Y3 |
Accessions | EAW96916 EAW96917 EAW96918 Q6ZMH5 AK172768 BAD18751 AK298331 BAG60580 AK313188 BAG36005 BC027884 AAH27884 DA640935 DA918133 XM_005268803 XP_005268860 XM_011538198 XP_011536500 XM_011538199 XP_011536501 XM_011538200 XP_011536502 XM_011538201 XP_011536503 XM_011538202 XP_011536504 XR_944520 NM_001135195 NP_001128667 NM_173596 NP_775867 |
Function | May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera (PubMed:24891338). Seems to play a central role in controlling organismal zinc status (By similarity). {ECO:0000250|UniProtKB:Q9D856, ECO:0000269|PubMed:24891338}. |
Subcellular Location | Basolateral cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney. {ECO:0000269|PubMed:15322118}. |
ZIP5 (H-83) - sc-368814 from Santa Cruz Biotechnology
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ZIP5 (N-16) - sc-109162 from Santa Cruz Biotechnology
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Anti-SLC39A5 antibody - ab105194 from Abcam
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Anti-SLC39A5 antibody - ab76191 from Abcam
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Anti-SLC39A5 antibody - ab69363 from Abcam
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Anti-SLC39A5 / ZIP5 Antibody (aa38-87) IHC-plus⢠- LS-B3557 from LifeSpan Bioscience
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Anti-SLC39A5 / ZIP5 Antibody (N-Terminus) - LS-C82473 from LifeSpan Bioscience
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Anti-SLC39A5 / ZIP5 Antibody (Internal) - LS-C115936 from LifeSpan Bioscience
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SLC39A5 Antibody - NBP1-69293 from Novus Biologicals
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SLC39A5 Antibody - NBP1-86044 from Novus Biologicals
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SLC39A5 Antibody - NBP1-69296 from Novus Biologicals
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SLC39A5 Antibody - H00283375-B01P from Novus Biologicals
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Anti-SLC39A5 (AB1) antibody produced in rabbit - AV44142 from Sigma-Aldrich
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Anti-SLC39A5, (N-terminal) antibody produced in mouse - SAB1408465 from Sigma-Aldrich
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Anti-SLC39A5 antibody produced in rabbit - HPA018423 from Sigma-Aldrich
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Anti-ZIP5 antibody produced in rabbit - SAB3500596 from Sigma-Aldrich
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Anti-SLC39A5 (AB2) antibody produced in rabbit - AV44143 from Sigma-Aldrich
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SLC39A5 antibody - N-terminal region (ARP44142_P050) - ARP44142_P050 from Aviva Systems Biology
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SLC39A5 antibody - N-terminal region (ARP44143_P050) - ARP44143_P050 from Aviva Systems Biology
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ZIP5 antibody - orb75534 from Biorbyt
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SLC39A5 antibody - 70R-7145 from Fitzgerald
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SLC39A5 antibody - 70R-7148 from Fitzgerald
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Zinc transporter ZIP5 / SLC39A5 (Center) antibody - AP26310PU-N from Acris Antibodies
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Zinc transporter ZIP5 / SLC39A5 antibody - H00283375-B01P from Acris Antibodies
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SLC39A5 Antibody - 25-932 from ProSci
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