CPSF6

Gene Symbol	CPSF6
Entrez Gene	11052
Alt Symbol	CFIM, CFIM68, HPBRII-4, HPBRII-7
Species	Human
Gene Type	protein-coding
Description	cleavage and polyadenylation specific factor 6, 68kDa
Other Description	CPSF 68 kDa subunit|cleavage and polyadenylation specificity factor 68 kDa subunit|cleavage and polyadenylation specificity factor subunit 6|cleavage factor Im complex 68 kDa subunit|pre-mRNA cleavage factor I, 68kD subunit|pre-mRNA cleavage factor Im (68kD)|pre-mRNA cleavage factor Im 68 kDa subunit|protein HPBRII-4/7
Swissprots	Q53ES1 Q9BW18 Q16630 Q9BSJ7 A8K7K9
Accessions	CAA47751 CCQ43384 EAW97215 EAW97216 EAW97217 EAW97218 EAW97219 Q16630 AK021534 AK021833 AK098338 AK223568 BAD97288 AK292024 BAF84713 AK299928 BAG61761 AW189370 BC000714 AAH00714 BC005000 AAH05000 DA365448 DQ892159 ABM83085 EU176688 ABW03489 X67337 CAA47752 XM_005268588 XP_005268645 XM_005268590 XP_005268647 NM_001300947 NP_001287876 NM_007007 NP_008938
Function	Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping. {ECO:0000269|PubMed:14690600, ECO:0000269|PubMed:20695905, ECO:0000269|PubMed:21295486, ECO:0000269|PubMed:8626397, ECO:0000269|PubMed:9659921}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:15169763, ECO:0000269|PubMed:20695905, ECO:0000269|PubMed:9659921}. Note=In punctate subnuclear structures localized adjacent to nuclear speckles, called paraspeckles.
Top Pathways	mRNA surveillance pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CFIm68 Gene - orb91995 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

CPSF6 - MBS1267208 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC000714

CPSF6 - MBS1276795 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC005000

Human CPSF6 ORF clone(NM_007007.2) - CDCL183706 from Creative Biomart Species Human Accession NM_007007.2

Human CPSF6 ORF Clone(NM_007007.2) - CDCL159657 from Creative Biomart Species Human Accession NM_007007.2

Human CPSF6 ORF Clone(NM_007007.2) - CDCL159658 from Creative Biomart Species Human Accession NM_007007.2

Human CPSF6 ORF Clone(NM_007007.2) - CDCR294181 from Creative Biomart Species Human Accession NM_007007.2

Human CPSF6 ORF Clone(NM_007007.2) - CDCR294182 from Creative Biomart Species Human Accession NM_007007.2

Human CPSF6 Gene cDNA clone plasmid - HG11458-M from Sino Biological Species Human

Human CPSF6 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11458-ACR from Sino Biological Species Human

Human CPSF6 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG11458-ANR from Sino Biological Species Human

Human CPSF6 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11458-CY from Sino Biological Species Human

Human CPSF6 Gene ORF cDNA clone expression plasmid - HG11458-UT from Sino Biological Species Human

Human CPSF6 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11458-NY from Sino Biological Species Human

Human CPSF6 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11458-ACG from Sino Biological Species Human

Human CPSF6 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG11458-ANG from Sino Biological Species Human

Human CPSF6 Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged - HG11458-M-F from Sino Biological Species Human Accession NM_007007.2

Human CPSF6 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG11458-M-N from Sino Biological Species Human Accession NM_007007.2

Human CPSF6 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11458-NF from Sino Biological Species Human

Human CPSF6 Gene ORF cDNA clone expression plasmid, C-His tag - HG11458-CH from Sino Biological Species Human

Human CPSF6 Gene ORF cDNA clone expression plasmid, N-His tag - HG11458-NH from Sino Biological Species Human

Human CPSF6 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11458-NM from Sino Biological Species Human

Human CPSF6 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11458-CF from Sino Biological Species Human

Human CPSF6 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11458-CM from Sino Biological Species Human

Human CPSF6 ORF clone(NM_007007.2) - CDCL183706 from Creative biogene Species Human

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