CPSF6

Gene Symbol CPSF6
Entrez Gene 11052
Alt Symbol CFIM, CFIM68, HPBRII-4, HPBRII-7
Species Human
Gene Type protein-coding
Description cleavage and polyadenylation specific factor 6, 68kDa
Other Description CPSF 68 kDa subunit|cleavage and polyadenylation specificity factor 68 kDa subunit|cleavage and polyadenylation specificity factor subunit 6|cleavage factor Im complex 68 kDa subunit|pre-mRNA cleavage factor I, 68kD subunit|pre-mRNA cleavage factor Im (68kD)|pre-mRNA cleavage factor Im 68 kDa subunit|protein HPBRII-4/7
Swissprots Q53ES1 Q9BW18 Q16630 Q9BSJ7 A8K7K9
Accessions CAA47751 CCQ43384 EAW97215 EAW97216 EAW97217 EAW97218 EAW97219 Q16630 AK021534 AK021833 AK098338 AK223568 BAD97288 AK292024 BAF84713 AK299928 BAG61761 AW189370 BC000714 AAH00714 BC005000 AAH05000 DA365448 DQ892159 ABM83085 EU176688 ABW03489 X67337 CAA47752 XM_005268588 XP_005268645 XM_005268590 XP_005268647 NM_001300947 NP_001287876 NM_007007 NP_008938
Function Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping. {ECO:0000269|PubMed:14690600, ECO:0000269|PubMed:20695905, ECO:0000269|PubMed:21295486, ECO:0000269|PubMed:8626397, ECO:0000269|PubMed:9659921}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15169763, ECO:0000269|PubMed:20695905, ECO:0000269|PubMed:9659921}. Note=In punctate subnuclear structures localized adjacent to nuclear speckles, called paraspeckles.
Top Pathways mRNA surveillance pathway

Human CPSF6 full length protein - ab161268 from Abcam

Category Protein
Source Wheat germ
Species Human
ab161268 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human CPSF6 protein fragment - ab161269 from Abcam

Category Protein
Source Wheat germ
Species Human
ab161269 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Recombinant Human CPSF6 Protein - H00011052-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human CPSF6 Protein - H00011052-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

CPSF6 Blocking Peptide - 33R-7262 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

CPSF6 - H00011052-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

CPSF6 - H00011052-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

CPSF6 - H00011052-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

CPSF6 - H00011052-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

CPSF6 fusion protein - Ag7852 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human CPSF6, GST-tagged - CPSF6-11540H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Cleavage and polyadenylation specificity factor subunit 6(CPSF6) - CSB-YP621966HU CSB-EP621966HU CSB-BP621966HU CSB-MP621966HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

CPSF6 - TP318138 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
CPSF6

Recombinant Human CPSF6 protein, MYC/DDK-tagged - CPSF6-1178H from Creative Biomart

Category Protein
Source HEK293
Species Human

Recombinant Human CPSF6 protein, GST-tagged - CPSF6-1849H from Creative Biomart

Category Protein
Source Wheat Germ
Species Human

Recombinant Human CPSF6 protein, GST-tagged - CPSF6-1848H from Creative Biomart

Category Protein
Source Wheat Germ
Species Human

CPSF6 Protein - NBP1-85676PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

CPSF6-Blocking-Peptide-N-term - BP20278a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CPSF6 Peptide, Human - M34GP03594H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Cleavage and polyadenylation specificity factor subunit 6 (CPSF6), Recombinant Protein - MBS1475120 from MyBioSource

Category Protein
Prices $1,345.00, $1,345.00, $1,565.00, $1,565.00, $2,230.00, $2,230.00, $2,695.00, $2,695.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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