Gene Symbol | COMMD6 |
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Entrez Gene | 170622 |
Alt Symbol | Acrg |
Species | Human |
Gene Type | protein-coding |
Description | COMM domain containing 6 |
Other Description | Acrg embryonic lethality minimal region ortholog|COMM domain-containing protein 6 |
Swissprots | A6NF28 Q7Z4G1 B7ZLN0 Q5TBK4 |
Accessions | EAW80539 EAW80540 EAW80541 Q7Z4G1 AA425275 AF086081 AF169971 AAQ13599 AK000009 AW516002 AY542161 AAS22243 BC110837 BC117391 AAI17392 BC143912 AAI43913 BC171758 AAI71758 BM476717 BX106312 BX538116 CD175553 DB487154 DB489071 DB509325 DB574884 HQ258699 ADR83450 HY028175 HY045286 HY105279 W94914 XM_011534948 XP_011533250 NM_001287392 NP_001274321 NM_001287393 NP_001274322 NM_001287394 NP_001274323 NM_203495 NP_987091 NM_203497 NP_987093 |
Function | May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Down-regulates activation of NF-kappa-B. Inhibits TNF-induced NFKB1 activation. {ECO:0000269|PubMed:15799966, ECO:0000269|PubMed:16573520, ECO:0000305|PubMed:21778237}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16573520, ECO:0000269|PubMed:21778237}. Cytoplasm {ECO:0000269|PubMed:16573520}. |
Tissue Specificity | Ubiquitous. Expressed in brain, heart, skeletal muscle, lung, pancreas, liver, kidney, small intestine and placenta. {ECO:0000269|PubMed:15799966, ECO:0000269|PubMed:16573520}. |
COMMD6 (A-12) - sc-84238 from Santa Cruz Biotechnology
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COMMD6 (N-14) - sc-84239 from Santa Cruz Biotechnology
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COMMD6 Antibody - NBP2-32520 from Novus Biologicals
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Anti-COMMD6 antibody produced in rabbit - HPA060266 from Sigma-Aldrich
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COMMD6 Antibody - 42937 from Signalway Antibody
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COMMD6 Antibody,Biotin conjugated - CSB-PA772019LD01HU from Cusabio
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COMMD6 Antibody,FITC conjugated - CSB-PA772019LC01HU from Cusabio
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COMMD6 Antibody,HRP conjugated - CSB-PA772019LB01HU from Cusabio
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COMMD6 Antibody - CSB-PA772019LA01HU from Cusabio
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COMMD6 antibody - orb360218 from Biorbyt
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COMMD6, Polyclonal Antibody - MBS7004929 from MyBioSource
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COMMD6, Polyclonal Antibody - MBS7002172 from MyBioSource
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COMMD6, Polyclonal Antibody - MBS7004496 from MyBioSource
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COMMD6, Polyclonal Antibody - MBS7004278 from MyBioSource
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COMMD6, Polyclonal Antibody - MBS9416403 from MyBioSource
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COMMD6 antibody - orb33757 from Biorbyt
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COMMD6 antibody (HRP) - orb33760 from Biorbyt
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COMMD6 antibody (FITC) - orb33763 from Biorbyt
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COMMD6 antibody (Biotin) - orb33767 from Biorbyt
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