COMMD6

Gene Symbol COMMD6
Entrez Gene 170622
Alt Symbol Acrg
Species Human
Gene Type protein-coding
Description COMM domain containing 6
Other Description Acrg embryonic lethality minimal region ortholog|COMM domain-containing protein 6
Swissprots A6NF28 Q7Z4G1 B7ZLN0 Q5TBK4
Accessions EAW80539 EAW80540 EAW80541 Q7Z4G1 AA425275 AF086081 AF169971 AAQ13599 AK000009 AW516002 AY542161 AAS22243 BC110837 BC117391 AAI17392 BC143912 AAI43913 BC171758 AAI71758 BM476717 BX106312 BX538116 CD175553 DB487154 DB489071 DB509325 DB574884 HQ258699 ADR83450 HY028175 HY045286 HY105279 W94914 XM_011534948 XP_011533250 NM_001287392 NP_001274321 NM_001287393 NP_001274322 NM_001287394 NP_001274323 NM_203495 NP_987091 NM_203497 NP_987093
Function May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Down-regulates activation of NF-kappa-B. Inhibits TNF-induced NFKB1 activation. {ECO:0000269|PubMed:15799966, ECO:0000269|PubMed:16573520, ECO:0000305|PubMed:21778237}.
Subcellular Location Nucleus {ECO:0000269|PubMed:16573520, ECO:0000269|PubMed:21778237}. Cytoplasm {ECO:0000269|PubMed:16573520}.
Tissue Specificity Ubiquitous. Expressed in brain, heart, skeletal muscle, lung, pancreas, liver, kidney, small intestine and placenta. {ECO:0000269|PubMed:15799966, ECO:0000269|PubMed:16573520}.

COMMD6 CRISPR/Cas9 KO Plasmid (h) - sc-414934 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

COMMD6 HDR Plasmid (h) - sc-414934-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

COMMD6 Double Nickase Plasmid (h) - sc-414934-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

COMMD6 Double Nickase Plasmid (h2) - sc-414934-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

COMMD6 CRISPR Activation Plasmid (h) - sc-414934-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

COMMD6 CRISPR Activation Plasmid (h2) - sc-414934-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

COMMD6 Lentiviral Activation Particles (h) - sc-414934-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

COMMD6 Lentiviral Activation Particles (h2) - sc-414934-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

COMMD6 siRNA (h) - sc-72966 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

COMMD6 shRNA Plasmid (h) - sc-72966-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

COMMD6 shRNA (h) Lentiviral Particles - sc-72966-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU124771 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6419 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6419 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09175 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09175

COMMD6 siRNA (Human) - CRJ6117 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

COMMD6 - MBS8236758 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human COMMD6 (NM_203495.2) - SHH267629 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human COMMD6(NM_203497.2) - SHG191845 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human COMMD6(NM_203495.2) - SHG191863 from Creative biogene

Category siRNA
Species Reactivities Human

COMMD6 shRNA Plasmid (Human) - CHJ6117 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

COMMD6 miRNA 3'UTR clone - MiUTR1H-02340 from Creative biogene

Species Reactivities Human

COMMD6 miRNA 3'UTR clone - MiUTR1H-02341 from Creative biogene

Species Reactivities Human
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