MAP2K3

Gene Symbol	MAP2K3
Entrez Gene	5606
Alt Symbol	MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2
Species	Human
Gene Type	protein-coding
Description	mitogen-activated protein kinase kinase 3
Other Description	MAP kinase kinase 3|MAPK/ERK kinase 3|MAPKK 3|MEK 3|SAPK kinase 2|dual specificity mitogen-activated protein kinase kinase 3|stress-activated protein kinase kinase 2
Swissprots	B3KSK7 P46734 Q9UE72 Q9UE71 Q99441
Accessions	AAB40653 EAW50386 P46734 AB451226 BAG70040 AB451349 BAG70163 AI758302 AK093838 BAG52769 AK223490 BAD97210 AK315505 BAG37889 BC032478 AAH32478 BM836867 CR536514 CAG38752 CR541793 CAG46592 D87116 BAA13248 DA131175 DA987047 DQ894188 ABM85114 GQ225578 ACT33197 L36719 AAC41718 U66839 AAB40652 XM_005256722 XP_005256779 XM_005256723 XP_005256780 XM_011523958 XP_011522260 XM_011523959 XP_011522261 NM_002756 NP_002747 NM_145109 NP_659731 NM_145110
Function	Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.
Tissue Specificity	Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
Top Pathways	Rap1 signaling pathway, Toll-like receptor signaling pathway, Inflammatory mediator regulation of TRP channels, TNF signaling pathway, Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence ® MKK3 siRNA II - 6295 from Cell Signaling Technology Category siRNA Prices $249.00 Sizes 300 µl (3 nmol)

SignalSilence ® MKK3 siRNA I - 6294 from Cell Signaling Technology Category siRNA Prices $249.00 Sizes 300 µl (3 nmol)

MEK-3 CRISPR/Cas9 KO Plasmid (h) - sc-401297 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK-3 HDR Plasmid (h) - sc-401297-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK-3 Double Nickase Plasmid (h) - sc-401297-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK-3 Double Nickase Plasmid (h2) - sc-401297-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK-3 CRISPR Activation Plasmid (h) - sc-401297-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK-3 CRISPR Activation Plasmid (h2) - sc-401297-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK-3 Lentiviral Activation Particles (h) - sc-401297-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK-3 Lentiviral Activation Particles (h2) - sc-401297-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK-3 siRNA (h) - sc-35907 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MEK-3 shRNA Plasmid (h) - sc-35907-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MEK-3 shRNA (h) Lentiviral Particles - sc-35907-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MEK-3/6 siRNA (h) - sc-43924 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MEK-3/6 shRNA Plasmid (h) - sc-43924-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MEK-3/6 shRNA (h) Lentiviral Particles - sc-43924-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MKK3/MEK3 RNAi - H00005606-R06 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MKK3/MEK3 RNAi - H00005606-R05 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MKK3/MEK3 RNAi - H00005606-R04 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU088281 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK1102 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1104 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1103 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN12983 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12983 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

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