Gene Symbol | MAP2K3 |
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Entrez Gene | 5606 |
Alt Symbol | MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2 |
Species | Human |
Gene Type | protein-coding |
Description | mitogen-activated protein kinase kinase 3 |
Other Description | MAP kinase kinase 3|MAPK/ERK kinase 3|MAPKK 3|MEK 3|SAPK kinase 2|dual specificity mitogen-activated protein kinase kinase 3|stress-activated protein kinase kinase 2 |
Swissprots | B3KSK7 P46734 Q9UE72 Q9UE71 Q99441 |
Accessions | AAB40653 EAW50386 P46734 AB451226 BAG70040 AB451349 BAG70163 AI758302 AK093838 BAG52769 AK223490 BAD97210 AK315505 BAG37889 BC032478 AAH32478 BM836867 CR536514 CAG38752 CR541793 CAG46592 D87116 BAA13248 DA131175 DA987047 DQ894188 ABM85114 GQ225578 ACT33197 L36719 AAC41718 U66839 AAB40652 XM_005256722 XP_005256779 XM_005256723 XP_005256780 XM_011523958 XP_011522260 XM_011523959 XP_011522261 NM_002756 NP_002747 NM_145109 NP_659731 NM_145110 |
Function | Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. |
Tissue Specificity | Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues. |
Top Pathways | Rap1 signaling pathway, Toll-like receptor signaling pathway, Inflammatory mediator regulation of TRP channels, TNF signaling pathway, Epstein-Barr virus infection |
Human MEK3 full length protein - ab132973 from Abcam
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Human MEK3 protein fragment - ab105578 from Abcam
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Human MEK3 protein fragment - ab125168 from Abcam
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MAP2K3 / MEK3 / MKK3 Antibody Blocking Peptide - LS-E3284 from LifeSpan Bioscience
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MAP2K3 / MEK3 / MKK3 Antibody Blocking Peptide - LS-E15480 from LifeSpan Bioscience
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MAP2K3 / MEK3 / MKK3 Antibody Blocking Peptide - LS-E15481 from LifeSpan Bioscience
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MKK3/MEK3 Recombinant Protein - H00005606-P01 from Novus Biologicals
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MKK3/MEK3 Partial Recombinant Protein - H00005606-Q01 from Novus Biologicals
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Recombinant Human MKK3/MEK3 Protein - NBP1-51069 from Novus Biologicals
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MKK3/MEK3 Peptide - P1356 from Novus Biologicals
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MKK3/MEK3 Peptide - P2897 from Novus Biologicals
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MKK3/MEK3 Peptide - P2896 from Novus Biologicals
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Phospho-MKK3S189-Antibody-Blocking-peptide - BP3170a from Abgent, a WuXi AppTec company
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MEK3-MAP2K3-Antibody-S189-Blocking-peptide - BP7915c from Abgent, a WuXi AppTec company
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MEK3-MAP2K3-Antibody-N-term-Blocking-peptide - BP7915a from Abgent, a WuXi AppTec company
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MAP2K3 Protein Lysate (APL10335) - APL10335 from Aviva Systems Biology
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Human MAP2K3 protein - orb168772 from Biorbyt
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Human MAP2K3 protein - orb246388 from Biorbyt
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MAP2K3 Blocking Peptide - 33R-2380 from Fitzgerald
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MAP2K3 Blocking Peptide - 33R-8564 from Fitzgerald
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MAP2K3 protein (His tag) - 80R-1757 from Fitzgerald
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Human MAP2K3 Protein - abx068036 from Abbexa
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MAP2K3 (1-318, His-tag) - AR09939PU-N from Acris Antibodies
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MAP2K3 (1-318, His-tag) - AR09939PU-S from Acris Antibodies
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MAP2K3 - H00005606-P01-10 from Acris Antibodies
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