DHRS3

Gene Symbol DHRS3
Entrez Gene 9249
Alt Symbol DD83.1, RDH17, Rsdr1, SDR1, SDR16C1, retSDR1
Species Human
Gene Type protein-coding
Description dehydrogenase/reductase (SDR family) member 3
Other Description retinal short-chain dehydrogenase/reductase 1|retinol dehydrogenase 17|short chain dehydrogenase/reductase family 16C member 1|short chain dehydrogenase/reductase family 16C, member 1|short-chain dehydrogenase/reductase 1|short-chain dehydrogenase/reductase 3
Swissprots Q6UY38 Q5VUY3 O75911 Q9BUC8 B2R7F3
Accessions AAD55402 ABY58122 EAW71743 O75911 AF061741 AAC63263 AK222593 BAD96313 AK225057 AK309282 AK310202 AK312961 BAG35800 AL039062 AY358093 AAQ88460 BC002730 AAH02730 BF037805 BX648476 CAI46033 DQ426869 ABD90534 DQ426870 ABD90535 DQ893006 ABM83932 DQ896252 ABM87251 XM_005263533 XP_005263590 XM_005263534 XP_005263591 XM_006711036 XP_006711099 NM_004753 NP_004744
Function Catalyzes the reduction of all-trans-retinal to all- trans-retinol in the presence of NADPH. {ECO:0000269|PubMed:9705317}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Widely expressed with highest levels found in heart, placenta, lung, liver, kidney, pancreas, thyroid, testis, stomach, trachea and spinal cord. Lower levels found in skeletal muscle, intestine and lymph node. No expression detected in brain. In the retina, expressed in cone but not rod outer segments. {ECO:0000269|PubMed:11861404, ECO:0000269|PubMed:9705317}.
Top Pathways Retinol metabolism

Anti-DHRS3 antibody - ab198005 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DHRS3 antibody (ab198005) at 1/550 dilutionLane 1 : Mouse liver tissue lysateLane 2 : A375 cell lysateLysates/proteins at 40 µg per lane.

Anti-DHRS3 antibody - ab95297 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-DHRS3 antibody (ab95297) at 1/100 dilution + HepG2 cell line lysate at 35 µg

Anti-DHRS3 antibody - ab69880 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-DHRS3 antibody (ab69880) at 1/500 dilutionLane 1 : DHRS3 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-DHRS3 / SDR1 Antibody (aa85-113, AP) - LS-C234565 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DHRS3 / SDR1 Antibody (aa85-113, APC) - LS-C234566 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DHRS3 / SDR1 Antibody (aa210-259) - LS-C145214 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DHRS3 antibody LS-C145214 Western blot of Mouse Spleen lysate. Antibody concentration 1 ug/ml.

Anti-DHRS3 / SDR1 Antibody (aa85-113, Biotin) - LS-C234567 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DHRS3 / SDR1 Antibody (aa85-113, FITC) - LS-C234569 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DHRS3 / SDR1 Antibody (aa85-113, PE) - LS-C234571 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DHRS3 / SDR1 Antibody (aa85-113, Azide-free, HRP) - LS-C249827 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DHRS3 / SDR1 Antibody - LS-C307242 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-DHRS3 / SDR1 Antibody (aa92-121) - LS-C320832 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DHRS3 / SDR1 Antibody (aa85-113) - LS-C167396 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of DHRS3 (arrow) using rabbit polyclonal DHRS3 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DHRS3 gene.

DHRS3 Antibody - NBP1-80846 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DHRS3 Antibody [NBP1-80846] - Lane 1: Mouse liver tissue lysate. Lane 2: Rat liver tissue lysate.

DHRS3 Antibody - H00009249-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: DHRS3 Antibody [H00009249-B01P] - Analysis of DHRS3 expression in transfected 293T cell line by DHRS3 polyclonal antibody. Lane 1: DHRS3 transfected lysate(33.22 KDa). Lane 2: Non-transfected lysate.

DHRS3 Polyclonal Antibody - bs-2286R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DHRS3 antibody produced in rabbit - HPA010844 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DHRS3: <B>Cat. No. HPA010844</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human colon shows strong cytoplasmic positivity in glandular cells.

Anti-DHRS3 antibody produced in mouse - SAB1406806 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-DHRS3: <B>Cat. No. SAB1406806</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~33.2 kDa using DHRS3 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

DHRS3-Antibody-Center - AP9188c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
DHRS3 Antibody (Center) (Cat. #AP9188c) western blot analysis in HepG2 cell line and mouse liver tissue lysates (35ug/lane).This demonstrates the DHRS3 antibody detected the DHRS3 protein (arrow).

DHRS3 Antibody - middle region (OAAB05779) - OAAB05779 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

DHRS3 antibody, Internal - GTX80507 from GeneTex

Prices $319.00
Sizes 400 μl
Host Rabbit
Clonality Polyclonal
Anti-DHRS3 antibody, Internal used in Western blot. GTX80507

DHRS3 antibody - orb4596 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal
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