Gene Symbol | DHRS3 |
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Entrez Gene | 9249 |
Alt Symbol | DD83.1, RDH17, Rsdr1, SDR1, SDR16C1, retSDR1 |
Species | Human |
Gene Type | protein-coding |
Description | dehydrogenase/reductase (SDR family) member 3 |
Other Description | retinal short-chain dehydrogenase/reductase 1|retinol dehydrogenase 17|short chain dehydrogenase/reductase family 16C member 1|short chain dehydrogenase/reductase family 16C, member 1|short-chain dehydrogenase/reductase 1|short-chain dehydrogenase/reductase 3 |
Swissprots | Q6UY38 Q5VUY3 O75911 Q9BUC8 B2R7F3 |
Accessions | AAD55402 ABY58122 EAW71743 O75911 AF061741 AAC63263 AK222593 BAD96313 AK225057 AK309282 AK310202 AK312961 BAG35800 AL039062 AY358093 AAQ88460 BC002730 AAH02730 BF037805 BX648476 CAI46033 DQ426869 ABD90534 DQ426870 ABD90535 DQ893006 ABM83932 DQ896252 ABM87251 XM_005263533 XP_005263590 XM_005263534 XP_005263591 XM_006711036 XP_006711099 NM_004753 NP_004744 |
Function | Catalyzes the reduction of all-trans-retinal to all- trans-retinol in the presence of NADPH. {ECO:0000269|PubMed:9705317}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Widely expressed with highest levels found in heart, placenta, lung, liver, kidney, pancreas, thyroid, testis, stomach, trachea and spinal cord. Lower levels found in skeletal muscle, intestine and lymph node. No expression detected in brain. In the retina, expressed in cone but not rod outer segments. {ECO:0000269|PubMed:11861404, ECO:0000269|PubMed:9705317}. |
Top Pathways | Retinol metabolism |
Human DHRS3 full length protein - ab160402 from Abcam
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DHRS3 / SDR1 Antibody Blocking Peptide - LS-E16947 from LifeSpan Bioscience
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DHRS3 / SDR1 Antibody Blocking Peptide - LS-E9993 from LifeSpan Bioscience
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Recombinant Human DHRS3 Protein - H00009249-P01 from Novus Biologicals
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DHRS3-Antibody-Center-Blocking-Peptide - BP9188c from Abgent, a WuXi AppTec company
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Dhrs3 Blocking Peptide - 33R-7138 from Fitzgerald
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DHRS3 - H00009249-P01-10 from Acris Antibodies
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DHRS3 - H00009249-P01-25 from Acris Antibodies
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DHRS3 fusion protein - Ag7589 from Proteintech Group
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DHRS3 fusion protein - ag7961 from Proteintech Group
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Recombinant Human DHRS3, GST-tagged - DHRS3-11975H from Creative Biomart
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Recombinant Neuroplastin (NPTN) - RPC666Hu01 from Cloud-clone
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DHRS3 Protein - abx164414 from Abbexa
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DHRS3 - TP301180 from Acris Antibodies
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DHRS3 Recombinant Protein Antigen - NBP1-80846PEP from Novus Biologicals
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DHRS3 Peptide, Human - M34GP04275H from Creative Peptides
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Short-chain dehydrogenase/reductase 3 (DHRS3), Recombinant Protein - MBS1083982 from MyBioSource
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Short-chain dehydrogenase/reductase 3 (DHRS3), Recombinant Protein - MBS7013767 from MyBioSource
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