TWIST1

Gene Symbol	TWIST1
Entrez Gene	7291
Alt Symbol	ACS3, BPES2, BPES3, CRS, CRS1, CSO, SCS, TWIST, bHLHa38
Species	Human
Gene Type	protein-coding
Description	twist family bHLH transcription factor 1
Other Description	B-HLH DNA binding protein|H-twist|TWIST homolog of drosophila|class A basic helix-loop-helix protein 38|twist basic helix-loop-helix transcription factor 1|twist homolog 1|twist-related protein 1
Swissprots	Q99804 Q92487 A4D128 Q15672
Accessions	AAC50930 AAC60381 CAA62850 CAA71821 EAL24279 EAW93711 Q15672 AW173505 BC036704 AAH36704 DQ896770 ABM87769 X99268 CAA67664 Y11177 Y11178 XM_011515496 XP_011513798 NM_000474 NP_000465
Function	Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation. Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus.
Tissue Specificity	Subset of mesodermal cells.
Top Pathways	Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TWIST1 / TWIST ELISA Kit (Sandwich ELISA) - LS-F8706 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.061 ng/ml Range 0.156-10 ng/ml

Twist Transcription Factor (TWIST), Human, ELISA Kit - SEC838Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.055ng/mL Range 0.156-10ng/mL

Twist-related protein 1 (TWIST1), Human, ELISA Kit - CSB-EL025358HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

TWIST1 (Human) IP-WB Antibody Pair - H00007291-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

TWIST1 (Human) IP-WB Antibody Pair - H00007291-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

TWIST1 (Human) IP-WB Antibody Pair - H00007291-PW3 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

TWIST1 (Human) IP-WB Antibody Pair - H00007291-PW4 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

twist homolog 1 (Drosophila) , ELISA Kit - MBS932173 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human TWIST1 is typically less than 6.25 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 25 pg/ml -1600 pg/ml.

ELISA Kit for Twist Transcription Factor (TWIST) - SEC838Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.061ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Twist-related protein 1(TWIST1) ELISA kit - CSB-EL025358HU from Cusabio Category ELISA Kit Sensitivity 6.25 pg/ml Range 25 pg/ml-1600 pg/ml

ELISA Kit for Twist Transcription Factor (TWIST) - SEC838Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.061ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human TWIST ELISA Kit - abx153412 from Abbexa Category ELISA Kit Sensitivity 0.055 ng/ml Range 0.156 ng/ml - 10 ng/ml

Twist Transcription Factor (TWIST), Human, ELISA Kit - DL-TWIST-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human TWIST1(Twist-related protein 1) ELISA Kit - E-EL-H5628 from Elabscience Category ELISA Kit Sensitivity 37.50 pg/mL Range 62.50—4000 pg/mL

Human TWIST ELISA Kit - abx571498 from Abbexa Category ELISA Kit Sensitivity 0.055 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human SCS ELISA Kit - E036864 from Biobool Category ELISA Kit

Human TWIST1 ELISA Kit - E040078 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human TWIST1 is typically less than 6.25 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the m

Human TWIST ELISA Kit - E040081 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of TWIST is typically less than 0.061ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding tw

TWIST ELISA Kit (Human) (OKDD00581) - OKDD00581 from Aviva Systems Biology Category ELISA Kit Prices $580.00 Sizes 96 wells Sensitivity < 0.055 ng/mL Range 0.156-10 ng/mL

anti-Twist1 antibody - ARG54909 from Arigo Biolaboratories Category ELISA Kit

Human TWIST1(Twist-related protein 1) ELISA Kit - E-EL-H5628 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 37.5 pg/mL Range 62.5~4000 pg/mL

Twist-Related Protein 1 (TWIST1), ELISA Kit - MBS9355422 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 1 (TWIST1), ELISA Kit - MBS9368243 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 1 (TWIST1), ELISA Kit - MBS9360017 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 1 (TWIST1), ELISA Kit - MBS9366912 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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