Gene Symbol | FGF19 |
---|---|
Entrez Gene | 9965 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | fibroblast growth factor 19 |
Other Description | FGF-19 |
Swissprots | O95750 |
Accessions | EAW74751 O95750 AB018122 BAA75500 AF110400 AAD45973 AY358302 AAQ88669 BC017664 AAH17664 BT006729 AAP35375 JF432499 ADZ15716 NM_005117 NP_005108 |
Function | Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. {ECO:0000269|PubMed:12815072, ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:17623664, ECO:0000269|PubMed:19085950}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in fetal brain, cartilage, retina, and adult gall bladder. {ECO:0000269|PubMed:10525310}. |
Top Pathways | Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton |
FGF19-Over-expression-Lysate - LY13933a from Abgent, a WuXi AppTec company
|
||||||||
FGF19 293T Cell Transient Overexpression Lysate(Denatured) - H00009965-T01 from Acris Antibodies
|
||||||||
FGF19 293T Cell Transient Overexpression Lysate(Denatured) - H00009965-T02 from Acris Antibodies
|
||||||||
FGF19 overexpression lysate - LY417507 from Acris Antibodies
|
||||||||
FGF19 293 Cell Lysate - 408194 from ABBIOTEC
|
||||||||
FGF-19 Overexpression Lysate (Denatured) - H00009965-T02 from Novus Biologicals
|
||||||||
FGF-19 Overexpression Lysate (Denatured) - H00009965-T01 from Novus Biologicals
|
||||||||
FGF-19 Overexpression Lysate (Native) - NBL1-10693 from Novus Biologicals
|
||||||||
FGF-19 (h): 293 Lysate - sc-112915 from Santa Cruz Biotechnology
|
||||||||
FGF19 Over-expression Lysate Product - GWB-C1DFB4 from Genway Biotech
|
||||||||
FGF-19 Overexpression Lysate (Denatured) - H00009965-T03 from Novus Biologicals
|
||||||||
Panoply™ Human FGF19 Knockdown Stable Cell Line - CSC-DC005702 from Creative biogene
|