FGF19

Gene Symbol FGF19
Entrez Gene 9965
Alt Symbol -
Species Human
Gene Type protein-coding
Description fibroblast growth factor 19
Other Description FGF-19
Swissprots O95750
Accessions EAW74751 O95750 AB018122 BAA75500 AF110400 AAD45973 AY358302 AAQ88669 BC017664 AAH17664 BT006729 AAP35375 JF432499 ADZ15716 NM_005117 NP_005108
Function Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. {ECO:0000269|PubMed:12815072, ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:17623664, ECO:0000269|PubMed:19085950}.
Subcellular Location Secreted.
Tissue Specificity Expressed in fetal brain, cartilage, retina, and adult gall bladder. {ECO:0000269|PubMed:10525310}.
Top Pathways Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton

Active human FGF19 full length protein - ab108946 from Abcam

Category Protein
Prices $315.00
Sizes 10 µg
Source HEK 293 cells
Species Human
ERK and FRS2a phosphorylation induced by FGF19 in Rat hepatoma cells. H4IIE Rat hepatoma cells were serum starved for 16hr and then stimulated with FGF-21-Fc or FGF-b (100ng/ml) (positive control) for 10 min, respectively. Antibodies against pFRS2a, pERK1/2 & total ERK1/2 were used for immunoblotting. Lane 1: control (non-treated) Lane 2: 30ng/ml hFGF19-His Lane 3: 100ng/ml hFGF19-His Lane 4: 300ng/ml hFGF19-His Lane 5: 1000ng/ml hFGF19-His Lane 6: 100ng/ml FGF-b

Active human FGF19 full length protein - ab200246 from Abcam

Category Protein
Prices $101.00
Sizes 5 µg
Source E. coli
Species Human

FGF19 peptide - ab93789 from Abcam

Category Peptide
Prices $176.00
Sizes 100 µg

Human FGF19 full length protein - ab55524 from Abcam

Category Protein
Source E. coli
Species Human

Human FGF19 full length protein - ab73213 from Abcam

Category Protein
Source E. coli
Species Human

Human FGF19 protein fragment - ab50132 from Abcam

Category Protein
Source E. coli
Species Human

Human FGF19 protein fragment - ab185824 from Abcam

Category Protein
Source E. coli
Species Human

FGF19 Antibody Blocking Peptide - LS-E5695 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

FGF19 Antibody Blocking Peptide - LS-E23243 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human FGF-19 Protein - NBP2-35013 from Novus Biologicals

Category Protein
Prices $69.00, $149.00, $2,700.00
Sizes 5 µg, 25 µg, 1 mg
Source E.coli
Species Human

FGF-19 Recombinant Protein - H00009965-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

FGF-19 Recombinant Protein - H00009965-P02 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

FGF-19 Recombinant Protein - P4089 from Novus Biologicals

Category Protein
Prices $549.00
Sizes 25 µg
Species Human

Recombinant Human FGF-19 Protein - NBP1-99420 from Novus Biologicals

Category Protein
Prices $190.00
Sizes 25 µg
Source E. coli
Species Human

FGF-19 Protein - NBP1-99661 from Novus Biologicals

Category Protein
Species Human

FGF19-Antibody-C-term-Blocking-Peptide - BP18231b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

FGF19 recombinant protein - GTX65308 from GeneTex

Category Protein
Prices $249.00
Sizes 25 μg
Source E. coli
Species Human
Anti-FGF-19 recombinant protein used in Western blot. GTX65308

FGF19 Recombinant Protein (Active) - GTX48324-PRO from GeneTex

Category Protein
Prices $299.00
Sizes 25 μg
Source E. coli
Species Human

Recombinant Human FGF-19 - 969-FG-025 from R&D Systems

Category Protein
Source E. coli-derived, Leu25-Lys216

Recombinant Human FGF-19, CF - 969-FG-025/CF from R&D Systems

Category Protein
Source E. coli-derived, Leu25-Lys216

Recombinant human Fibroblast growth factor 19 protein (OPCA00646) - OPCA00646 from Aviva Systems Biology

Category Protein
Prices $220.00
Sizes 50 µg
Species Human

FGF 19 Protein (OPPA00544) - OPPA00544 from Aviva Systems Biology

Category Protein
Prices $100.00
Sizes 5 µg
Source E. Coli

FGF 19 Protein (OPPA01883) - OPPA01883 from Aviva Systems Biology

Category Protein
Prices $100.00
Sizes 5 µg
Source E. Coli

Human FGF-19 protein - orb245287 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

Human FGF 19 protein - orb138859 from Biorbyt

Category Protein
Prices $298.00, $434.00
Sizes 20 μg, 50 μg
Source E. coli
Species Human
SDS-PAGE analysis of human FGF19 protein (Native)
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