FGF19

Gene Symbol FGF19
Entrez Gene 9965
Alt Symbol -
Species Human
Gene Type protein-coding
Description fibroblast growth factor 19
Other Description FGF-19
Swissprots O95750
Accessions EAW74751 O95750 AB018122 BAA75500 AF110400 AAD45973 AY358302 AAQ88669 BC017664 AAH17664 BT006729 AAP35375 JF432499 ADZ15716 NM_005117 NP_005108
Function Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. {ECO:0000269|PubMed:12815072, ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:17623664, ECO:0000269|PubMed:19085950}.
Subcellular Location Secreted.
Tissue Specificity Expressed in fetal brain, cartilage, retina, and adult gall bladder. {ECO:0000269|PubMed:10525310}.
Top Pathways Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton

FGF-19 CRISPR/Cas9 KO Plasmid (h) - sc-401725 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGF-19 HDR Plasmid (h) - sc-401725-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGF-19 Double Nickase Plasmid (h) - sc-401725-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGF-19 Double Nickase Plasmid (h2) - sc-401725-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGF-19 CRISPR Activation Plasmid (h) - sc-401725-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGF-19 CRISPR Activation Plasmid (h2) - sc-401725-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGF-19 Lentiviral Activation Particles (h) - sc-401725-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGF-19 Lentiviral Activation Particles (h2) - sc-401725-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGF-19 siRNA (h) - sc-39480 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FGF-19 shRNA Plasmid (h) - sc-39480-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FGF-19 shRNA (h) Lentiviral Particles - sc-39480-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FGF-19 RNAi - H00009965-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU027451 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8654 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8654 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR13063 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr13063

FGF19 siRNA (Human) - CRH6702 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FGF19 - MBS8208800 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FGF-19 CRISPR/Cas9 KO Plasmid (h2) - sc-401725-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGF-19 HDR Plasmid (h2) - sc-401725-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human FGF19 (NM_005117.2) - SHH294477 from Creative biogene

Category siRNA
Species Reactivities Human

FGF19 shRNA Plasmid (Human) - CHH6702 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FGF19 miRNA 3'UTR clone - MiUTR1H-03627 from Creative biogene

Species Reactivities Human
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