PTP4A3

Gene Symbol PTP4A3
Entrez Gene 11156
Alt Symbol PRL-3, PRL-R, PRL3
Species Human
Gene Type protein-coding
Description protein tyrosine phosphatase type IVA, member 3
Other Description potentially prenylated protein tyrosine phosphatase|protein tyrosine phosphatase type IVA 3|protein-tyrosine phosphatase 4a3|protein-tyrosine phosphatase of regenerating liver 3
Swissprots Q8IVN5 Q9BTW5 O75365 Q99849
Accessions EAW92231 O75365 AF041434 AAC29314 AI742376 AJ276554 CAC81757 AK311257 BC003105 AAH03105 BE778111 BQ637038 BT007303 AAP35967 U87168 AAB47560 XM_005250762 XP_005250819 XM_005250763 XP_005250820 XM_005250764 XP_005250821 XM_005250766 XP_005250823 XM_005250767 XP_005250824 XM_006716499 XP_006716562 XM_006716500 XP_006716563 XM_006725100 XP_006725163 XM_006725101 XP_006725164 XM_006725102 XP_006725165 XM_006725103 XP_006725166 XM_011516803 XP_011515105 XM_011516804 XP_011515106 XM_011516805 XP_011515107 XM_011546558 XP_011544860 XM_011546559 XP_011544861 XM_011546560 XP_011544862 XM_011546561 XP_011544863 NM_007079 NP_009010 NM_032611 NP_116000
Function Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. {ECO:0000269|PubMed:11355880, ECO:0000269|PubMed:12782572}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:12782572}. Early endosome {ECO:0000269|PubMed:12782572}.
Tissue Specificity Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis. {ECO:0000269|PubMed:11355880}.

PTP4A3 Antibody - 6484 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from human, mouse, and rat muscle tissues using PTP4A3 Antibody.

PRL-1/2/3 (FL-173) - sc-33197 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PRL-1/2/3 (FL-173): sc-33197. Western blot analysis of PRL-1/2/3 expression in rat brain tissue extract.

PRL-3 (318) - sc-130355 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

PRL-3 (D-18) - sc-21581 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PRL-3 (D-18): sc-21581. Immunoperoxidase staining of formalin fixed, paraffin-embedded human heart muscle tissue showing cytoplasmic staining of myocytes.

PRL-3 (111AT714) - sc-130245 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
PRL-3 (111AT714): sc-130245. Western blot analysis of PRL-3 expression in 293 whole cell lysate.

Anti-PTP4A3 antibody - ab50276 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PTP4A3 antibody - ab82568 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PTP4A3 antibody (ab82568) at 1 µg/mlLane 1 : Heart (Human) Tissue Lysate - adult normal tissue (ab29431)Lane 2 : Skeletal Muscle (Human) Tissue Lysate - adult normal tissue (ab29330)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-PTP4A3 antibody - ab26947 from Abcam

Prices $370.00
Sizes 125 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PTP4A3 antibody (ab26947) at 1/5000 dilutionLane 1 : (T2.5) IPTG induction of the recombinant protein expression for 2.5 hours.Lane 2 : (T0) before IPTG induction of the protein expression

Anti-PTP4A3 antibody - ab135688 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PTP4A3 antibody (ab135688) at 1/100 dilution + Mouse heart tissue lysate at 35 µg

Anti-PTP4A3 antibody - ab2449 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
PTP4A3 antibody (ab2449) at 0.03 µg/ml + Human Pancreas lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Anti-PTP4A3 antibody [111AT714] - ab38673 from Abcam

Prices $304.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 111AT714
Anti-PTP4A3 antibody [111AT714] (ab38673) at 1/100 dilution + 293 cells transfected with PTP4A3 at 35 µg

Anti-PTP4A3 Antibody - LS-C96162 from LifeSpan Bioscience

Prices $345.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-PTP4A3 Antibody - LS-C101019 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of PRL3 Antibody in mouse heart tissue lysates (35 ug/lane). PRL3 (arrow) was detected using the purified antibody.

Anti-PTP4A3 Antibody (N-Terminus) - LS-C20198 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Staining (2 ug/ml) of Human Pancreas lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

Anti-PTP4A3 Antibody (C-Terminus, AP) - LS-C226190 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTP4A3 Antibody (C-Terminus) - LS-C101020 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of PTP4A3 C-term in MCF-7 and 293 cell line lysates (35 ug/lane). PTP4A3 (arrow) was detected using the purified antibody.

Anti-PTP4A3 Antibody (C-Terminus, Biotin) - LS-C226191 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTP4A3 Antibody (C-Terminus, FITC) - LS-C226192 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTP4A3 Antibody (C-Terminus, APC) - LS-C226193 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTP4A3 Antibody (C-Terminus, Azide-free, HRP) - LS-C226194 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTP4A3 Antibody (clone 111AT714) - LS-C96501 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Mouse
Clonality Monoclonal
Clone 111AT714
The monoclonal antibody anti-PRL3 is used in Western blot to detect PRL3 in 293 cells transfected with PRL3.

Anti-PTP4A3 Antibody (C-Terminus, PE) - LS-C226195 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTP4A3 Antibody (AP) - LS-C226196 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTP4A3 Antibody (APC) - LS-C226197 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTP4A3 Antibody (C-Terminus) - LS-C111303 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PTP4A3 antibody LS-C111303 Western blot of 293T cell lysate.
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