PTP4A3

Gene Symbol PTP4A3
Entrez Gene 11156
Alt Symbol PRL-3, PRL-R, PRL3
Species Human
Gene Type protein-coding
Description protein tyrosine phosphatase type IVA, member 3
Other Description potentially prenylated protein tyrosine phosphatase|protein tyrosine phosphatase type IVA 3|protein-tyrosine phosphatase 4a3|protein-tyrosine phosphatase of regenerating liver 3
Swissprots Q8IVN5 Q9BTW5 O75365 Q99849
Accessions EAW92231 O75365 AF041434 AAC29314 AI742376 AJ276554 CAC81757 AK311257 BC003105 AAH03105 BE778111 BQ637038 BT007303 AAP35967 U87168 AAB47560 XM_005250762 XP_005250819 XM_005250763 XP_005250820 XM_005250764 XP_005250821 XM_005250766 XP_005250823 XM_005250767 XP_005250824 XM_006716499 XP_006716562 XM_006716500 XP_006716563 XM_006725100 XP_006725163 XM_006725101 XP_006725164 XM_006725102 XP_006725165 XM_006725103 XP_006725166 XM_011516803 XP_011515105 XM_011516804 XP_011515106 XM_011516805 XP_011515107 XM_011546558 XP_011544860 XM_011546559 XP_011544861 XM_011546560 XP_011544862 XM_011546561 XP_011544863 NM_007079 NP_009010 NM_032611 NP_116000
Function Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. {ECO:0000269|PubMed:11355880, ECO:0000269|PubMed:12782572}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:12782572}. Early endosome {ECO:0000269|PubMed:12782572}.
Tissue Specificity Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis. {ECO:0000269|PubMed:11355880}.

Human PTP4A3 full length protein - ab87716 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE showing ab87716 at approximately 21.6kDa (3µg).

Human PTP4A3 full length protein - ab42570 from Abcam

Category Protein
Source E. coli
Species Human

Human PTP4A3 peptide - ab93307 from Abcam

Category Peptide

Human PTP4A3 peptide - ab22906 from Abcam

Category Peptide
Species Human

PTP4A3 Antibody Blocking Peptide - LS-E25295 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PTP4A3 Antibody Blocking Peptide - LS-E18427 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PTP4A3 Antibody Blocking Peptide - LS-E9580 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PTP4A3 Antibody Blocking Peptide - LS-E17511 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PRL-3/PTP4A3 Recombinant Protein - H00011156-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human PRL-3/PTP4A3 Protein - NBP1-30246 from Novus Biologicals

Category Protein
Prices $229.00
Sizes 100 µg
Species Human
SDS-Page: PRL-3 Protein [NBP1-30246] - PRL-3, 21.6 kDa (193aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

PRL-3/PTP4A3 Peptide - P3272 from Novus Biologicals

Category Peptide
Species Human

PRL3-Antibody-C-term-Blocking-Peptide - BP8438b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PTP4A3 blocking peptide - GTX89930-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Mouse, Rat

Recombinant Human PRL-3/PTP4A3, CF - 8455-PT-050 from R&D Systems

Category Protein
Source E. coli-derived, Ala2-Met173, with N-terminal Met and 7-His tag

PTP4A3 Protein (OPPA01962) - OPPA01962 from Aviva Systems Biology

Category Protein
Prices $100.00
Sizes 10 µg
Source E. Coli

Human Prolactin Receptor protein - orb80565 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 5 μg, 20 μg
Source E.coli

Human Protein Tyrosine Phosphatase Type IVA Member 3 protein - orb90257 from Biorbyt

Category Protein
Prices $230.00, $442.00
Sizes 10 μg, 50 μg
Source E.coli
Species Human

Human PRL-R protein - orb180585 from Biorbyt

Category Protein
Prices $697.00
Sizes 5 μg
Source E. coli
Species Human

Human Prolactin Receptor GST Tag protein - orb80564 from Biorbyt

Category Protein
Prices $366.00, $400.00, $621.00
Sizes 5 μg, 2 μg, 10 μg
Source E.coli

PRL3 protein (His tag) - 80R-1203 from Fitzgerald

Category Protein
Prices $180.00
Sizes 100 µg
Source E.coli

PTP4A3 Blocking Peptide - 33R-4993 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

PTP4A3 Blocking Peptide - 33R-6174 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

PTP4A3 Peptide - AC21-0123-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

PRL3 / PTP4A3 (1-173, His-tag) - AR09281PU-L from Acris Antibodies

Category Protein
Prices $585.00
Sizes 500 µg
Source E. coli
Species Human
Recombinant human PRL-3, 1-173 aa, His-tagged: 15% SDS-PAGE (3 µg)

PRL3 / PTP4A3 (1-173, His-tag) - AR09281PU-N from Acris Antibodies

Category Protein
Prices $270.00
Sizes 100 µg
Source E. coli
Species Human
Recombinant human PRL-3, 1-173 aa, His-tagged: 15% SDS-PAGE (3 µg)
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