PTP4A3

Gene Symbol PTP4A3
Entrez Gene 11156
Alt Symbol PRL-3, PRL-R, PRL3
Species Human
Gene Type protein-coding
Description protein tyrosine phosphatase type IVA, member 3
Other Description potentially prenylated protein tyrosine phosphatase|protein tyrosine phosphatase type IVA 3|protein-tyrosine phosphatase 4a3|protein-tyrosine phosphatase of regenerating liver 3
Swissprots Q8IVN5 Q9BTW5 O75365 Q99849
Accessions EAW92231 O75365 AF041434 AAC29314 AI742376 AJ276554 CAC81757 AK311257 BC003105 AAH03105 BE778111 BQ637038 BT007303 AAP35967 U87168 AAB47560 XM_005250762 XP_005250819 XM_005250763 XP_005250820 XM_005250764 XP_005250821 XM_005250766 XP_005250823 XM_005250767 XP_005250824 XM_006716499 XP_006716562 XM_006716500 XP_006716563 XM_006725100 XP_006725163 XM_006725101 XP_006725164 XM_006725102 XP_006725165 XM_006725103 XP_006725166 XM_011516803 XP_011515105 XM_011516804 XP_011515106 XM_011516805 XP_011515107 XM_011546558 XP_011544860 XM_011546559 XP_011544861 XM_011546560 XP_011544862 XM_011546561 XP_011544863 NM_007079 NP_009010 NM_032611 NP_116000
Function Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. {ECO:0000269|PubMed:11355880, ECO:0000269|PubMed:12782572}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:12782572}. Early endosome {ECO:0000269|PubMed:12782572}.
Tissue Specificity Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis. {ECO:0000269|PubMed:11355880}.

PTP4A3-Over-expression-Lysate - LY10539a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag PTP4A3 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PTP4A3 gene (Lane 2, Cat. #LY10539a).

PTP4A3 overexpression lysate - LY410006 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

PTP4A3 overexpression lysate - LY416216 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

PTP4A3 293 Cell Lysate - 407590 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

PTP4A3 293 Cell Lysate - 405162 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

PRL-3/PTP4A3 Overexpression Lysate (Native) - NBL1-14961 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: PRL-3 Overexpression Lysate (Adult Normal) [NBL1-14961] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PRL-3.

PRL-3/PTP4A3 Overexpression Lysate (Native) - NBP2-05990 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

PTP4A3 Over-expression Lysate Product - GWB-55A7E7 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

PTP4A3 Over-expression Lysate Product - GWB-3DD7AD from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Panoply™ Human PTP4A3 Knockdown Stable Cell Line - CSC-DC012687 from Creative biogene

Category Cell Line
Species Human
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