Gene Symbol | GAK |
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Entrez Gene | 2580 |
Alt Symbol | DNAJ26, DNAJC26 |
Species | Human |
Gene Type | protein-coding |
Description | cyclin G associated kinase |
Other Description | auxilin-2|cyclin-G-associated kinase |
Swissprots | Q5U4P5 Q9BVY6 O14976 |
Accessions | EAW82644 EAW82645 EAW82646 O14976 AB208854 BAD92091 AK092587 AK097714 BAG53518 AK126735 BAC86662 AK127351 AK131464 BAD18609 AK299554 BAG61499 AK309413 BC000816 AAH00816 BC001290 BC008668 AAH08668 BC063606 AAH63606 BC085005 AAH85005 BC107076 AAI07077 BT007015 AAP35661 D88435 BAA22623 DA680073 XM_005272268 XP_005272325 XM_005272270 XP_005272327 XM_011513425 XP_011511727 XM_011513426 XP_011511728 XM_011513427 XP_011511729 XM_011513428 XP_011511730 XM_011513429 XP_011511731 XM_011513430 XP_011511732 XM_011513431 XP_011511733 XM_011513432 XP_011511734 XM_011513433 XP_011511735 XM_011513434 XP_011511736 NM_001286833 NP_001273762 NM_005255 NP_005246 |
Function | Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. {ECO:0000269|PubMed:10625686}. |
Subcellular Location | Cytoplasm, perinuclear region {ECO:0000269|PubMed:10625686}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:10625686}. Cell junction, focal adhesion {ECO:0000305|PubMed:10625686}. Note=Localizes to the perinuclear area and to the trans-Golgi network. Also seen on the plasma membrane, probably at focal adhesions. |
Tissue Specificity | Ubiquitous. Highest in testis. |
Human GAK protein fragment - ab114800 from Abcam
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Human GAK protein fragment - ab132270 from Abcam
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GAK Antibody Blocking Peptide - LS-E9462 from LifeSpan Bioscience
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Recombinant Human GAK Protein - H00002580-P01 from Novus Biologicals
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Recombinant Human GAK Protein - H00002580-Q01 from Novus Biologicals
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GAK Peptide - P3054 from Novus Biologicals
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GAK Peptide - P3053 from Novus Biologicals
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GAK-Antibody-N-term-Blocking-Peptide - BP8061a from Abgent, a WuXi AppTec company
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GAK-Antibody-C-term-Blocking-Peptide - BP8061b from Abgent, a WuXi AppTec company
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GAK - H00002580-P01-10 from Acris Antibodies
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GAK - H00002580-P01-25 from Acris Antibodies
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GAK - H00002580-Q01-10 from Acris Antibodies
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GAK - H00002580-Q01-25 from Acris Antibodies
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GAK fusion protein - ag2795 from Proteintech Group
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Recombinant Human GAK protein, GST-tagged - GAK-28312TH from Creative Biomart
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GAK Blocking Peptide - CBP3952 from Cohesion Biosciences
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GAK (Q129) Peptide - BS1871P from Bioworld Technology
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Recombinant Human Cyclin-G-associated kinase(GAK) ,partial - CSB-YP009190HU CSB-EP009190HU CSB-BP009190HU CSB-MP009190HU from Cusabio
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GAK - TP323572 from Acris Antibodies
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GAK Recombinant Protein Antigen - NBP1-89441PEP from Novus Biologicals
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GAK Blocking Peptide - abx162445 from Abbexa
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GAK Recombinant Protein Antigen - NBP1-86389PEP from Novus Biologicals
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GAK Recombinant Protein Antigen - NBP1-86388PEP from Novus Biologicals
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GAK-Antibody-Center-Blocking-Peptide - BP8061c from Abgent, a WuXi AppTec company
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GAK Peptide, Human - M34GP06062H from Creative Peptides
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