GAK

Gene Symbol GAK
Entrez Gene 2580
Alt Symbol DNAJ26, DNAJC26
Species Human
Gene Type protein-coding
Description cyclin G associated kinase
Other Description auxilin-2|cyclin-G-associated kinase
Swissprots Q5U4P5 Q9BVY6 O14976
Accessions EAW82644 EAW82645 EAW82646 O14976 AB208854 BAD92091 AK092587 AK097714 BAG53518 AK126735 BAC86662 AK127351 AK131464 BAD18609 AK299554 BAG61499 AK309413 BC000816 AAH00816 BC001290 BC008668 AAH08668 BC063606 AAH63606 BC085005 AAH85005 BC107076 AAI07077 BT007015 AAP35661 D88435 BAA22623 DA680073 XM_005272268 XP_005272325 XM_005272270 XP_005272327 XM_011513425 XP_011511727 XM_011513426 XP_011511728 XM_011513427 XP_011511729 XM_011513428 XP_011511730 XM_011513429 XP_011511731 XM_011513430 XP_011511732 XM_011513431 XP_011511733 XM_011513432 XP_011511734 XM_011513433 XP_011511735 XM_011513434 XP_011511736 NM_001286833 NP_001273762 NM_005255 NP_005246
Function Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. {ECO:0000269|PubMed:10625686}.
Subcellular Location Cytoplasm, perinuclear region {ECO:0000269|PubMed:10625686}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:10625686}. Cell junction, focal adhesion {ECO:0000305|PubMed:10625686}. Note=Localizes to the perinuclear area and to the trans-Golgi network. Also seen on the plasma membrane, probably at focal adhesions.
Tissue Specificity Ubiquitous. Highest in testis.

GAK CRISPR/Cas9 KO Plasmid (h) - sc-404235 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAK HDR Plasmid (h) - sc-404235-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAK Double Nickase Plasmid (h) - sc-404235-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAK Double Nickase Plasmid (h2) - sc-404235-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAK CRISPR Activation Plasmid (h) - sc-404235-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAK CRISPR Activation Plasmid (h2) - sc-404235-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAK Lentiviral Activation Particles (h) - sc-404235-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAK Lentiviral Activation Particles (h2) - sc-404235-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAK siRNA (h) - sc-43791 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GAK shRNA Plasmid (h) - sc-43791-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GAK shRNA (h) Lentiviral Particles - sc-43791-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GAK RNAi - H00002580-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU158381 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK0827 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0829 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0828 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN9089 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9089 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02999 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02999

GAK siRNA (Human) - CRH1716 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GAK - MBS8223941 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GAK (NM_005255.2) - SHH298809 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human GAK(NM_005255.2) - SHH075305 from Creative biogene

Category siRNA
Species Reactivities Human

GAK shRNA Plasmid (Human) - CHH1716 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GAK miRNA 3'UTR clone - MiUTR1H-03926 from Creative biogene

Species Reactivities Human
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