Gene Symbol | MAP3K1 |
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Entrez Gene | 4214 |
Alt Symbol | MAPKKK1, MEKK, MEKK 1, MEKK1, SRXY6 |
Species | Human |
Gene Type | protein-coding |
Description | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
Other Description | MAP/ERK kinase kinase 1|MAPK/ERK kinase kinase 1|MEK kinase 1|mitogen-activated protein kinase kinase kinase 1 |
Swissprots | Q13233 |
Accessions | AAB05828 CCQ43342 Q13233 AA602425 AF042838 AAC97073 AK307828 BU194120 BX537527 DA889202 XM_005248519 XP_005248576 XM_011543406 XP_011541708 XM_011543407 XP_011541709 XM_011543408 XP_011541710 NM_005921 NP_005912 |
Function | Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway. {ECO:0000269|PubMed:9808624}. |
Top Pathways | Ubiquitin mediated proteolysis, GnRH signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway, RIG-I-like receptor signaling pathway |
Active human MEKK1 protein fragment - ab104027 from Abcam
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Human MEKK1 protein fragment - ab152522 from Abcam
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MAP3K1 / MEKK1 Antibody Blocking Peptide - LS-E3445 from LifeSpan Bioscience
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MAP3K1 / MEKK1 Antibody Blocking Peptide - LS-E7343 from LifeSpan Bioscience
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MAP3K1 / MEKK1 Antibody Blocking Peptide - LS-E17599 from LifeSpan Bioscience
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MAP3K1 / MEKK1 Antibody Blocking Peptide - LS-E9362 from LifeSpan Bioscience
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Recombinant Human MEKK1 Protein - H00004214-Q01 from Novus Biologicals
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MEKK1 Peptide - P1474 from Novus Biologicals
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MEKK1 Peptide - P2885 from Novus Biologicals
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Phospho-MAP3K1T1383-Antibody-Blocking-peptide - BP3321a from Abgent, a WuXi AppTec company
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MEKK1-Antibody-C-term-Blocking-Peptide - BP7907a from Abgent, a WuXi AppTec company
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Mouse Map3k1 protein - orb245619 from Biorbyt
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MAP3K1 Blocking Peptide - 33R-4960 from Fitzgerald
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MAP3K1 - H00004214-Q01-10 from Acris Antibodies
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MAP3K1 - H00004214-Q01-25 from Acris Antibodies
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MAP3K1 - P5588 from Acris Antibodies
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Recombinant Human MAP3K1 - MAP3K1-30190TH from Creative Biomart
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Recombinant Human Mitogen-Activated Protein Kinase Kinase Kinase 1, GST-Tagged - MAP3K1-1037H from Creative Biomart
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Recombinant Mitogen Activated Protein Kinase Kinase Kinase 1 (MAP3K1) - RPB145Hu01 from Uscn Life Science Inc.
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MEKK1 (pT1402) Blocking Peptide - CBP4072 from Cohesion Biosciences
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MEK Kinase-1 (W197) Peptide - BS9126P from Bioworld Technology
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Recombinant Mitogen Activated Protein Kinase Kinase Kinase 1 (MAP3K1) - RPB145Hu01 from Cloud-clone
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Recombinant mouse Mitogen-activated protein kinase kinase kinase 1 - CSB-EP152874m CSB-BP152874m CSB-MP152874m from Cusabio
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Recombinant Mouse Mitogen-activated protein kinase kinase kinase 1(MAP3K1),partial - CSB-RP152874m from Cusabio
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Recombinant Human Mitogen-activated protein kinase kinase kinase 1(MAP3K1) ,part - CSB-YP013417HU CSB-EP013417HU CSB-BP013417HU CSB-MP013417HU from Cusabio
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