MAP3K1

Gene Symbol	MAP3K1
Entrez Gene	4214
Alt Symbol	MAPKKK1, MEKK, MEKK 1, MEKK1, SRXY6
Species	Human
Gene Type	protein-coding
Description	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
Other Description	MAP/ERK kinase kinase 1|MAPK/ERK kinase kinase 1|MEK kinase 1|mitogen-activated protein kinase kinase kinase 1
Swissprots	Q13233
Accessions	AAB05828 CCQ43342 Q13233 AA602425 AF042838 AAC97073 AK307828 BU194120 BX537527 DA889202 XM_005248519 XP_005248576 XM_011543406 XP_011541708 XM_011543407 XP_011541709 XM_011543408 XP_011541710 NM_005921 NP_005912
Function	Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway. {ECO:0000269|PubMed:9808624}.
Top Pathways	Ubiquitin mediated proteolysis, GnRH signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway, RIG-I-like receptor signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MEK Kinase 1 CRISPR/Cas9 KO Plasmid (h) - sc-401107 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK Kinase 1 HDR Plasmid (h) - sc-401107-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK Kinase 1 Double Nickase Plasmid (h) - sc-401107-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK Kinase 1 Double Nickase Plasmid (h2) - sc-401107-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK Kinase 1 CRISPR Activation Plasmid (h) - sc-401107-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK Kinase 1 CRISPR Activation Plasmid (h2) - sc-401107-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK Kinase 1 Lentiviral Activation Particles (h) - sc-401107-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK Kinase 1 Lentiviral Activation Particles (h2) - sc-401107-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK kinase-1 siRNA (h) - sc-35898 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MEK kinase-1 shRNA Plasmid (h) - sc-35898-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MEK kinase-1 shRNA (h) Lentiviral Particles - sc-35898-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU057091 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® siRNA - SIHK1122 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1117 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1119 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1121 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1118 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1120 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN12987 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12987 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MAP3K1 siRNA (Human) - CRH2865 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

MEKK1 RNAi - H00004214-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

shRNA set against Human MAP3K1 (NM_005921.1) - SHH337607 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human MAP3K1(NM_005921.1) - SHH173783 from Creative biogene Category siRNA Species Reactivities Human

Human MAP3K1 siRNA - orb263367 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

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