WBP11

Gene Symbol	WBP11
Entrez Gene	51729
Alt Symbol	NPWBP, PPP1R165, SIPP1, WBP-11
Species	Human
Gene Type	protein-coding
Description	WW domain binding protein 11
Other Description	Npw38-binding protein NpwBP|SH3 domain-binding protein SNP70|WW domain-binding protein 11|protein phosphatase 1, regulatory subunit 165|splicing factor that interacts with PQBP-1 and PP1|splicing factor, PQBP1 and PP1 interacting
Swissprots	Q96AY8 Q9Y2W2
Accessions	EAW96328 EAW96329 Q9Y2W2 AB029309 BAA88410 AF118023 AAD30425 AK297410 BAG59845 AK302244 BAG63596 BC001621 AAH01621 BC016441 AAH16441 BC023532 AAH23532 BX647347 DQ892540 ABM83466 DQ895751 ABM86677 NM_016312 NP_057396
Function	Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity. {ECO:0000269|PubMed:10593949, ECO:0000269|PubMed:11375989, ECO:0000269|PubMed:14640981}.
Subcellular Location	Nucleus. Cytoplasm. Note=Predominantly located in the nucleus with granular heterogeneous distribution. Excluded from nucleoli in interphase cells, distributed throughout cytoplasm in dividing cells. Colocalized with SC35 and U2B in the nucleus. In the cytoplasm, associates with the intermediate filament protein vimentin.
Tissue Specificity	Ubiquitous. Highly expressed in the heart, pancreas, kidney skeletal muscle, placenta and brain (at protein level). Weakly expressed in liver and lung. {ECO:0000269|PubMed:11375989}.
Top Pathways	Spliceosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human WBP11 full length protein - ab162652 from Abcam Category Protein Source Wheat germ Species Human

WBP11 Antibody Blocking Peptide - LS-E16869 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

WBP11 Recombinant Protein - H00051729-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

WBP11 Blocking Peptide - 33R-3541 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

WBP11 - H00051729-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

WBP11 - H00051729-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

WBP11 fusion protein - ag0366 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human WW domain-binding protein 11(WBP11) - CSB-YP896881HU CSB-EP896881HU CSB-BP896881HU CSB-MP896881HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

WW domain-binding protein 11 (WBP11) , Recombinant Protein - MBS1428199 from MyBioSource Category Protein Prices $2,440.00, $2,440.00, $2,860.00, $2,860.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

WBP11 Recombinant Protein Antigen - NBP2-38602PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

WBP11 Recombinant Protein Antigen - NBP2-38551PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

WBP11 Recombinant Protein Antigen - NBP1-80988PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

WBP11 Peptide, Human - M34GP17383H from Creative Peptides Category Peptide Source Synthetic. Species Human

WBP11 Recombinant Protein Antigen - NBP2-58142PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

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