WBP11

Gene Symbol WBP11
Entrez Gene 51729
Alt Symbol NPWBP, PPP1R165, SIPP1, WBP-11
Species Human
Gene Type protein-coding
Description WW domain binding protein 11
Other Description Npw38-binding protein NpwBP|SH3 domain-binding protein SNP70|WW domain-binding protein 11|protein phosphatase 1, regulatory subunit 165|splicing factor that interacts with PQBP-1 and PP1|splicing factor, PQBP1 and PP1 interacting
Swissprots Q96AY8 Q9Y2W2
Accessions EAW96328 EAW96329 Q9Y2W2 AB029309 BAA88410 AF118023 AAD30425 AK297410 BAG59845 AK302244 BAG63596 BC001621 AAH01621 BC016441 AAH16441 BC023532 AAH23532 BX647347 DQ892540 ABM83466 DQ895751 ABM86677 NM_016312 NP_057396
Function Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity. {ECO:0000269|PubMed:10593949, ECO:0000269|PubMed:11375989, ECO:0000269|PubMed:14640981}.
Subcellular Location Nucleus. Cytoplasm. Note=Predominantly located in the nucleus with granular heterogeneous distribution. Excluded from nucleoli in interphase cells, distributed throughout cytoplasm in dividing cells. Colocalized with SC35 and U2B in the nucleus. In the cytoplasm, associates with the intermediate filament protein vimentin.
Tissue Specificity Ubiquitous. Highly expressed in the heart, pancreas, kidney skeletal muscle, placenta and brain (at protein level). Weakly expressed in liver and lung. {ECO:0000269|PubMed:11375989}.
Top Pathways Spliceosome

NPWBP (F-1) - sc-393556 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NPWBP (F-1): sc-393556. Western blot analysis of NPWBP expression in non-transfected: sc-117752 (A) and mouse NPWBP transfected: sc-122117 (B) 293T whole cell lysates.

NPWBP (N-12) - sc-161959 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NPWBP (N-12): sc-161959. Western blot analysis of NPWBP expression in non-transfected: sc-117752 (A) and mouse NPWBP transfected: sc-122117 (B) 293T whole cell lysates.

NPWBP (S-12) - sc-161960 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NPWBP (S-12): sc-161960. Western blot analysis of NPWBP expression in non-transfected: sc-117752 (A) and mouse NPWBP transfected: sc-122117 (B) 293T whole cell lysates.

Anti-WBP11 antibody - ab154590 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-WBP11 antibody (ab154590) at 1/2000 dilutionLane 1 : Jurkat whole cell lysateLane 2 : Raji whole cell lysateLane 3 : K562 whole cell lysateLane 4 : THP1 whole cell lysateLane 5 : HL60 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-WBP11 antibody - ab85563 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human pineal tissue labelling WBP11 with ab85563 at 1/100. A Cy3-conjugate donkey anti-rabbit IgG (1/200) was used as the secondary antibody. Positive staining shown in the cytoplasm of the cell bodies of pinealocytes and their processes. Magnification: 20X. Exposure time: 0.5 - 2.0 seconds. Left - DAPI. Middle - WBP11. Right - Merge.

Anti-WBP11 antibody - ab69352 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-WBP11 antibody (ab69352) at 1/500 dilutionLane 1 : WBP11 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-WBP11 Antibody (N-Terminus) - LS-C102213 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
WBP11 antibody LS-C102213 Western blot of HeLa lysate.

Anti-WBP11 Antibody - LS-C332570 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using WBP11 antibody.

WBP11 Antibody - NBP1-54648 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: WBP11 Antibody [NBP1-54648] - Titration: 2 ug/ml Positive Control: Human NT-2 cells and Mouse WT brain.

WBP11 Antibody - NBP2-20886 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: WBP11 Antibody [NBP2-20886] - Whole cell extracts (30 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with WBP11 antibody diluted by 1:2000.

WBP11 Antibody - NBP2-38602 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: WBP11 Antibody [NBP2-38602] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.

WBP11 Antibody - NBP2-38551 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: WBP11 Antibody [NBP2-38551] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10Lane 2: Human cell line NTERA-2

WBP11 Antibody - H00051729-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

WBP11 Antibody - NBP1-80988 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-WBP11 antibody produced in rabbit - SAB2102692 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-WBP11: <B>Cat. No.SAB2102692</B>: WBP11 in HeLa cell lysate with WBP11 antibody at 1.0 μg/mL.

Anti-WBP11 antibody produced in mouse - SAB1407520 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-WBP11: <B>Cat. No. SAB1407520</B>: Antibody concentration: 10 μg/mL using HeLa cell.

Anti-WBP11 antibody produced in rabbit - HPA040037 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-WBP11: <B>Cat. No. HPA040037</B>: Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

WBP11 antibody - N-terminal region (ARP46241_P050) - ARP46241_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LINC01553 antibody (Biotin) - orb22468 from Biorbyt

Prices $357.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of Hela(Lane1),Y79(Lane2),K562(Lane3),Ramos(Lane4),Jurkat(Lane5) in whole lysates using WBP11 antibody

WBP11 antibody - 70R-2408 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

WBP11 Polyclonal Antibody - A3437 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using WBP11 antibody.

WBP11 antibody - 70R-21297 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

WBP11 Antibody - abx002466 from Abbexa

Host Rabbit
Clonality Polyclonal

WBP11 Antibody - abx007638 from Abbexa

Host Rabbit
Clonality Polyclonal

WBP11 antibody - 10316-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Mouse heart tissue were subjected to SDS PAGE followed by western blot with 10316-1-AP(WBP11 antibody) at dilution of 1:1000
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