WBP11

Gene Symbol WBP11
Entrez Gene 51729
Alt Symbol NPWBP, PPP1R165, SIPP1, WBP-11
Species Human
Gene Type protein-coding
Description WW domain binding protein 11
Other Description Npw38-binding protein NpwBP|SH3 domain-binding protein SNP70|WW domain-binding protein 11|protein phosphatase 1, regulatory subunit 165|splicing factor that interacts with PQBP-1 and PP1|splicing factor, PQBP1 and PP1 interacting
Swissprots Q96AY8 Q9Y2W2
Accessions EAW96328 EAW96329 Q9Y2W2 AB029309 BAA88410 AF118023 AAD30425 AK297410 BAG59845 AK302244 BAG63596 BC001621 AAH01621 BC016441 AAH16441 BC023532 AAH23532 BX647347 DQ892540 ABM83466 DQ895751 ABM86677 NM_016312 NP_057396
Function Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity. {ECO:0000269|PubMed:10593949, ECO:0000269|PubMed:11375989, ECO:0000269|PubMed:14640981}.
Subcellular Location Nucleus. Cytoplasm. Note=Predominantly located in the nucleus with granular heterogeneous distribution. Excluded from nucleoli in interphase cells, distributed throughout cytoplasm in dividing cells. Colocalized with SC35 and U2B in the nucleus. In the cytoplasm, associates with the intermediate filament protein vimentin.
Tissue Specificity Ubiquitous. Highly expressed in the heart, pancreas, kidney skeletal muscle, placenta and brain (at protein level). Weakly expressed in liver and lung. {ECO:0000269|PubMed:11375989}.
Top Pathways Spliceosome

NPWBP CRISPR/Cas9 KO Plasmid (h) - sc-409953 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NPWBP HDR Plasmid (h) - sc-409953-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NPWBP Double Nickase Plasmid (h) - sc-409953-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NPWBP Double Nickase Plasmid (h2) - sc-409953-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NPWBP CRISPR Activation Plasmid (h) - sc-409953-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NPWBP CRISPR Activation Plasmid (h2) - sc-409953-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NPWBP Lentiviral Activation Particles (h) - sc-409953-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NPWBP Lentiviral Activation Particles (h2) - sc-409953-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NPWBP siRNA (h) - sc-95727 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NPWBP shRNA Plasmid (h) - sc-95727-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NPWBP shRNA (h) Lentiviral Particles - sc-95727-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

WBP11 RNAi - H00051729-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU104691 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22786 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22786 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05543 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05543

WBP11 siRNA (Human) - CRH9922 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

WBP11 - MBS8207925 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human WBP11 (NM_016312.2) - SHH445684 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human WBP11(NM_016312.2) - SHL129954 from Creative biogene

Category siRNA
Species Reactivities Human

WBP11 shRNA Plasmid (Human) - CHH9922 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

WBP11 miRNA 3'UTR clone - MiUTR1H-11188 from Creative biogene

Species Reactivities Human
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