NDNL2

Gene Symbol NDNL2
Entrez Gene 56160
Alt Symbol HCA4, MAGEG1, MAGEL3, NSE3, NSMCE3
Species Human
Gene Type protein-coding
Description necdin-like 2
Other Description MAGE-G1 antigen|hepatocellular carcinoma-associated protein 4|hepatocellular carcinoma-associated protein HCA4|melanoma antigen, family G, 1|melanoma-associated antigen G1|necdin-like gene 2|necdin-like protein 2
Swissprots Q9H214 Q8TEI6 Q96MG7 Q8IW16
Accessions AAG38607 EAW51515 Q96MG7 AF490510 AAM08357 AK056957 BAB71325 AK074138 BAB84964 AU310582 BC035458 BC041166 AAH41166 BC053999 AAH53999 NM_138704 NP_619649
Function Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). In vitro enhances ubiquitin ligase activity of NSMCE1. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May be a growth suppressor that facilitates the entry of the cell into cell cycle arrest. {ECO:0000269|PubMed:20864041}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000269|PubMed:18086888}. Chromosome, telomere {ECO:0000305|PubMed:18086888}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:11782285}.

MAGE-G1 CRISPR/Cas9 KO Plasmid (h) - sc-412689 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAGE-G1 HDR Plasmid (h) - sc-412689-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAGE-G1 Double Nickase Plasmid (h) - sc-412689-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAGE-G1 Double Nickase Plasmid (h2) - sc-412689-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAGE-G1 CRISPR Activation Plasmid (h) - sc-412689-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAGE-G1 CRISPR Activation Plasmid (h2) - sc-412689-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAGE-G1 Lentiviral Activation Particles (h) - sc-412689-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAGE-G1 Lentiviral Activation Particles (h2) - sc-412689-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAGE-G1 siRNA (h) - sc-90118 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MAGE-G1 shRNA Plasmid (h) - sc-90118-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MAGE-G1 shRNA (h) Lentiviral Particles - sc-90118-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU036281 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15123 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15123 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12237 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12237

NDNL2 siRNA (Human) - CRJ1098 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NDNL2 (NM_138704.3) - SHH350328 from Creative biogene

Category siRNA
Species Reactivities Human

Human NDNL2 siRNA - orb271599 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NDNL2 shRNA Plasmid (Human) - CHJ1098 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NDNL2 miRNA 3'UTR clone - MiUTR3H-09866 from Creative biogene

Species Reactivities Human
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