CYSLTR1

Gene Symbol	CYSLTR1
Entrez Gene	10800
Alt Symbol	CYSLT1, CYSLT1R, CYSLTR, HMTMF81
Species	Human
Gene Type	protein-coding
Description	cysteinyl leukotriene receptor 1
Other Description	G-protein coupled receptor HG55|LTD4 receptor|cysteinyl leukotriene D4 receptor
Swissprots	Q5JS94 Q8IV19 Q9Y271 D3DTE4 B2R954
Accessions	AAO92297 CAC38932 CCF76997 EAW98598 EAW98599 Q9Y271 AF119711 AAD42285 AF133266 AAD42778 AK023929 AK313643 BAG36401 BC035750 AAH35750 DQ131799 ABA01563 DQ131800 ABA01564 DQ131801 ABA01565 DQ131802 ABA01566 DQ131803 ABA01567 DQ890947 ABM81873 EU176542 ABW03343 NM_001282186 NP_001269115 NM_001282187 NP_001269116 NM_001282188 NP_001269117 NM_006639 NP_006630
Function	Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Widely expressed, with highest levels in spleen and peripheral blood leukocytes. Lower expression in several tissues, such as lung (mostly in smooth muscle bundles and alveolar macrophages), placenta, small intestine, pancreas, colon and heart.
Top Pathways	Calcium signaling pathway, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CYSLTR1 / CYSLT1 ELISA Kit (Sandwich ELISA) - LS-F8033 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.135 ng/ml Range 0.313-20 ng/ml

Human CYSLTR1 ELISA Kit - abx151230 from Abbexa Category ELISA Kit Sensitivity 0.135 ng/ml Range 0.313 ng/ml - 20 ng/ml

Cysteinyl Leukotriene Receptor 1, CYSLTR1, Human, ELISA Kit - E-EL-H0999 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.188 Range 0.313-20ng/mL

Cysteinyl leukotriene receptor 1 (CYSLTR1), Human, ELISA Kit - CSB-EL006465HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Cysteinyl Leukotriene Receptor 1 (CYSLTR1), Human, ELISA Kit - SEC424Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.135ng/mL Range 0.312-20ng/mL

Cysteinyl leukotriene receptor 1 (CYSLTR1), Human, ELISA Kit - E01C2264 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Cysteinyl Leukotriene Receptor 1, CYSLTR1, Rabbit, ELISA Kit - E-EL-RB1221 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Cysteinyl Leukotriene Receptor 1, CYSLTR1, Chicken, ELISA Kit - E-EL-Ch0048 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t

Cysteinyl Leukotriene Receptor 1, CYSLTR1, Porcine, ELISA Kit - E-EL-P0622 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Cysteinyl Leukotriene Receptor 1, CYSLTR1, Guinea Pig, ELISA Kit - E-EL-GP0923 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Cysteinyl Leukotriene Receptor 1, CYSLTR1, Monkey, ELISA Kit - E-EL-MK0314 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human CYSLTR1(Cysteinyl Leukotriene Receptor 1) ELISA Kit - E-EL-H0999 from Elabscience Category ELISA Kit Sensitivity 0.19 ng/mL Range 0.31—20 ng/mL

Human CYSLTR1 (Cysteinyl Leukotriene Receptor 1) CLIA Kit - E-CL-H0673 from Elabscience Category CLIA Kit Sensitivity 37.50 pg/mL Range Average Recovery (%)

CYSLTR1, ELISA Kit - MBS2511989 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

CYSLTR1, ELISA Kit - MBS2503335 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

CYSLTR1, ELISA Kit - MBS2505166 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

CYSLTR1, ELISA Kit - MBS2514650 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 75pg/mL Range 125-8000pg/mL

CYSLTR1, ELISA Kit - MBS2506987 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313--20ng/mL

CYSLTR1, ELISA Kit - MBS2511358 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Cysteinyl Leukotriene Receptor 1, ELISA Kit - MBS083992 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteinyl Leukotriene Receptor 1, ELISA Kit - MBS063534 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

cysteinyl leukotriene receptor 1, ELISA Kit - MBS937022 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human CYSLTR1 is typically less than 6.2 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 25 pg/ml -1600 pg/ml.

Cysteinyl Leukotriene Receptor 1, ELISA Kit - MBS104018 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteinyl Leukotriene Receptor 1, ELISA Kit - MBS098931 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteinyl Leukotriene Receptor 1, ELISA Kit - MBS071590 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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