CYSLTR1

Gene Symbol	CYSLTR1
Entrez Gene	10800
Alt Symbol	CYSLT1, CYSLT1R, CYSLTR, HMTMF81
Species	Human
Gene Type	protein-coding
Description	cysteinyl leukotriene receptor 1
Other Description	G-protein coupled receptor HG55|LTD4 receptor|cysteinyl leukotriene D4 receptor
Swissprots	Q5JS94 Q8IV19 Q9Y271 D3DTE4 B2R954
Accessions	AAO92297 CAC38932 CCF76997 EAW98598 EAW98599 Q9Y271 AF119711 AAD42285 AF133266 AAD42778 AK023929 AK313643 BAG36401 BC035750 AAH35750 DQ131799 ABA01563 DQ131800 ABA01564 DQ131801 ABA01565 DQ131802 ABA01566 DQ131803 ABA01567 DQ890947 ABM81873 EU176542 ABW03343 NM_001282186 NP_001269115 NM_001282187 NP_001269116 NM_001282188 NP_001269117 NM_006639 NP_006630
Function	Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Widely expressed, with highest levels in spleen and peripheral blood leukocytes. Lower expression in several tissues, such as lung (mostly in smooth muscle bundles and alveolar macrophages), placenta, small intestine, pancreas, colon and heart.
Top Pathways	Calcium signaling pathway, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CysLT1 full length protein - ab153131 from Abcam Category Protein Source Wheat germ Species Human

Human CysLT1 protein fragment - ab153132 from Abcam Category Protein Source Wheat germ Species Human

CYSLTR1 / CYSLT1 Antibody Blocking Peptide - LS-E3610 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CYSLTR1 / CYSLT1 Antibody Blocking Peptide - LS-E22441 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CYSLTR1 / CYSLT1 Antibody Blocking Peptide - LS-E28235 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CYSLTR1 / CYSLT1 Antibody Blocking Peptide - LS-E28236 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human Cysteinyl Leukotriene R1/CysLTR1 Protein - H00010800-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Cysteinyl Leukotriene R1/CysLTR1 Protein - H00010800-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

CYSLTR1-Antibody-Center-Blocking-Peptide - BP14813c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CYSLTR1 Blocking Peptide - abx063703 from Abbexa Category Peptide Species Human, Monkey

CYSLTR1 - H00010800-G01 from Acris Antibodies Category Protein Prices $440.00 Sizes 2 µg Species Human

CYSLTR1 - H00010800-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

CYSLTR1 - H00010800-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CYSLTR1 - H00010800-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CYSLTR1 fusion protein - ag6233 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Cysteinyl Leukotriene Receptor 1 (CYSLTR1) - RPC424Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

ChemiSCREEN™ Membrane Preparation Recombinant Human CysLT 1 Cysteinyl Leukotriene Receptor - HTS061M from EMD Millipore Prices $599.00 Sizes 200 units Species Human

CYSLTR1 Blocking Peptide - CBP2509 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Monkey

CysLTR1 (C173) Peptide - BS2592P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

CysLTR1 (K172) Peptide - BS2711P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Cysteinyl Leukotriene Receptor 1 (CYSLTR1) - RPC424Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Cysteinyl Leukotriene R1/CysLTR1 Protein - H00010800-G01 from Novus Biologicals Category Protein Prices $415.00 Sizes 2 µg Source Wheat Germ Species Human

Cysteinyl Leukotriene R1/CysLTR1 Protein - NBP1-85356PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

CYSLTR1 Blocking Peptide - abx061364 from Abbexa Category Peptide Species Human, Monkey

CYSLTR1 Peptide, Human - M34GP03993H from Creative Peptides Category Peptide Source Synthetic. Species Human

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