Gene Symbol | LTN1 |
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Entrez Gene | 26046 |
Alt Symbol | C21orf10, C21orf98, RNF160, ZNF294 |
Species | Human |
Gene Type | protein-coding |
Description | listerin E3 ubiquitin protein ligase 1 |
Other Description | E3 ubiquitin-protein ligase listerin|ring finger protein 160|zinc finger protein 294 |
Swissprots | A6NL41 O94822 Q9H8M4 Q05C47 A7E2D0 C9J7U3 Q9P0E9 Q9NUY5 B2RTS0 J3KPL4 |
Accessions | CAB90429 CAB90430 EAX09935 EAX09936 EAX09937 O94822 AB018257 BAA34434 AB621822 BAK64157 AF161350 AAF28910 AK001915 BAA91976 AK023499 BAB14589 BC007525 BC029371 AAH29371 BC031633 BC045726 BC140790 AAI40791 BC150284 AAI50285 BF059116 DB452437 XM_006723987 XP_006724050 XM_011529525 XP_011527827 NM_015565 NP_056380 |
Function | E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23685075, PubMed:25132172, PubMed:25578875). Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity). {ECO:0000250|UniProtKB:Q04781, ECO:0000269|PubMed:23685075, ECO:0000269|PubMed:25132172, ECO:0000269|PubMed:25578875}. |
ZNF294 (N-20) - sc-83353 from Santa Cruz Biotechnology
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Anti-RNF160 antibody - ab104375 from Abcam
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Anti-RNF160 antibody - N-terminal - ab189540 from Abcam
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Anti-LTN1 / RNF160 Antibody (aa1087-1115, AP) - LS-C240097 from LifeSpan Bioscience
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Anti-LTN1 / RNF160 Antibody (aa1087-1115, Biotin) - LS-C240098 from LifeSpan Bioscience
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Anti-LTN1 / RNF160 Antibody (aa1087-1115, APC) - LS-C240099 from LifeSpan Bioscience
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Anti-LTN1 / RNF160 Antibody (aa1087-1115, FITC) - LS-C240100 from LifeSpan Bioscience
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Anti-LTN1 / RNF160 Antibody (aa1087-1115, PE) - LS-C240101 from LifeSpan Bioscience
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Anti-LTN1 / RNF160 Antibody (aa1087-1115, Azide-free, HRP) - LS-C248021 from LifeSpan Bioscience
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Anti-LTN1 / RNF160 Antibody (aa1086-1115) - LS-C324728 from LifeSpan Bioscience
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Anti-LTN1 / RNF160 Antibody (aa1087-1115) - LS-C162650 from LifeSpan Bioscience
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Anti-LTN1 / RNF160 Antibody (aa47-96) - LS-C116229 from LifeSpan Bioscience
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RNF160 Antibody - NBP1-89879 from Novus Biologicals
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RNF160 Antibody - NBP2-33341 from Novus Biologicals
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RNF160 Polyclonal Antibody - bs-8376R from Bioss
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ANTI-RNF160 (CENTER) antibody produced in rabbit - SAB1305130 from Sigma-Aldrich
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Anti-LTN1 antibody produced in rabbit - HPA029143 from Sigma-Aldrich
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Anti-ZNF294, (N-terminal) antibody produced in rabbit - SAB2105503 from Sigma-Aldrich
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ZNF294 antibody - N-terminal region (ARP43201_P050) - ARP43201_P050 from Aviva Systems Biology
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RNF160-Antibody-Center - AP16206c from Abgent, a WuXi AppTec company
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RNF160 Antibody - middle region (OAAB11604) - OAAB11604 from Aviva Systems Biology
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ZNF294 antibody - 70R-2768 from Fitzgerald
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RNF160 Antibody - abx028661 from Abbexa
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RNF160 / ZNF294 (Center) antibody - AP53685PU-N from Acris Antibodies
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ZNF294 Antibody - GWB-MP402F from Genway Biotech
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