LTN1

Gene Symbol LTN1
Entrez Gene 26046
Alt Symbol C21orf10, C21orf98, RNF160, ZNF294
Species Human
Gene Type protein-coding
Description listerin E3 ubiquitin protein ligase 1
Other Description E3 ubiquitin-protein ligase listerin|ring finger protein 160|zinc finger protein 294
Swissprots A6NL41 O94822 Q9H8M4 Q05C47 A7E2D0 C9J7U3 Q9P0E9 Q9NUY5 B2RTS0 J3KPL4
Accessions CAB90429 CAB90430 EAX09935 EAX09936 EAX09937 O94822 AB018257 BAA34434 AB621822 BAK64157 AF161350 AAF28910 AK001915 BAA91976 AK023499 BAB14589 BC007525 BC029371 AAH29371 BC031633 BC045726 BC140790 AAI40791 BC150284 AAI50285 BF059116 DB452437 XM_006723987 XP_006724050 XM_011529525 XP_011527827 NM_015565 NP_056380
Function E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23685075, PubMed:25132172, PubMed:25578875). Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity). {ECO:0000250|UniProtKB:Q04781, ECO:0000269|PubMed:23685075, ECO:0000269|PubMed:25132172, ECO:0000269|PubMed:25578875}.

Panoply™ Human LTN1 Knockdown Stable Cell Line - CSC-DC008988 from Creative biogene

Category Cell Line
Species Human
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