Gene Symbol | ITGB6 |
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Entrez Gene | 3694 |
Alt Symbol | AI1H |
Species | Human |
Gene Type | protein-coding |
Description | integrin, beta 6 |
Other Description | integrin beta-6 |
Swissprots | P18564 B2R9W5 Q53RG5 Q16500 Q0VA95 Q53RR6 C9JA97 |
Accessions | AAB23690 AAX93093 AAY24053 CAA01832 EAX11390 P18564 AI264144 AK026736 AK290300 BAF82989 AK304203 BAG65080 AK313944 BAG36662 AL359053 AL831998 AM393800 CAL38675 BC121178 AAI21179 BC143656 CD013944 CD013945 CD013946 CD013947 DB222211 M35198 AAA36122 NM_000888 NP_000879 NM_001282353 NP_001269282 NM_001282354 NP_001269283 NM_001282355 NP_001269284 NM_001282388 NP_001269317 NM_001282389 NP_001269318 NM_001282390 NP_001269319 |
Function | Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. {ECO:0000269|PubMed:17545607}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Focal adhesion, ECM-receptor interaction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy |
Human ITGB6 full length protein - ab116827 from Abcam
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Human ITGB6 full length protein - ab183569 from Abcam
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Human ITGB6 protein fragment - ab158778 from Abcam
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Recombinant Human Integrin beta 6 Protein - H00003694-P01 from Novus Biologicals
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Recombinant Human Integrin beta 6 Protein - H00003694-Q01 from Novus Biologicals
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ITGB6-Antibody-C-term-Blocking-peptide - BP5684b from Abgent, a WuXi AppTec company
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Integrin beta-6 / ITGB6 - H00003694-P01 from Acris Antibodies
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Integrin beta-6 / ITGB6 - H00003694-Q01-10 from Acris Antibodies
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Integrin beta-6 / ITGB6 - H00003694-Q01-25 from Acris Antibodies
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Integrin beta-6 fusion protein - Ag17394 from Proteintech Group
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Integrin beta-6 fusion protein - ag16319 from Proteintech Group
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Recombinant Human ITGB6 - ITGB6-29868TH from Creative Biomart
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Recombinant Integrin Beta 6 (ITGb6) - RPC099Hu01 from Uscn Life Science Inc.
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Recombinant Integrin Beta 6 (ITGb6) - RPC099Mu01 from Uscn Life Science Inc.
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Recombinant Human Integrin beta-6(ITGB6) - CSB-YP011890HU CSB-EP011890HU CSB-BP011890HU CSB-MP011890HU from Cusabio
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Integrin beta-6 / ITGB6 - TP317387 from Acris Antibodies
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Integrin beta 6 Recombinant Protein Antigen - NBP2-14136PEP from Novus Biologicals
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ITGB6 Peptide, Human - M34GP07809H from Creative Peptides
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ITGB6 Recombinant Protein (OPCD04601) - OPCD04601 from Aviva Systems Biology
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Integrin alpha V beta 6 Recombinant Protein - 96-906 from ProSci
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Integrin Beta 6, Recombinant Protein - MBS2029193 from MyBioSource
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Integrin Beta 6, Recombinant Protein - MBS2031288 from MyBioSource
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Integrin beta-6, Recombinant Protein - MBS7042961 from MyBioSource
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Integrin beta-6 (ITGB6), Recombinant Protein - MBS955945 from MyBioSource
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