ITGB6

Gene Symbol ITGB6
Entrez Gene 3694
Alt Symbol AI1H
Species Human
Gene Type protein-coding
Description integrin, beta 6
Other Description integrin beta-6
Swissprots P18564 B2R9W5 Q53RG5 Q16500 Q0VA95 Q53RR6 C9JA97
Accessions AAB23690 AAX93093 AAY24053 CAA01832 EAX11390 P18564 AI264144 AK026736 AK290300 BAF82989 AK304203 BAG65080 AK313944 BAG36662 AL359053 AL831998 AM393800 CAL38675 BC121178 AAI21179 BC143656 CD013944 CD013945 CD013946 CD013947 DB222211 M35198 AAA36122 NM_000888 NP_000879 NM_001282353 NP_001269282 NM_001282354 NP_001269283 NM_001282355 NP_001269284 NM_001282388 NP_001269317 NM_001282389 NP_001269318 NM_001282390 NP_001269319
Function Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. {ECO:0000269|PubMed:17545607}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways Focal adhesion, ECM-receptor interaction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

Integrin β6 (H-110) - sc-15329 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Integrin &betta;6 (H-110): sc-15329. Immunofluorescence staining of normal mouse heart frozen section showing membrane staining.

Integrin β6 (C-19) - sc-6632 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Integrin β6 Antibody (C-19): sc-6632. Immunoperoxidase staining of formalin fixed, paraffin-embedded human rectum tissue showing cytoplasmic staining of glandular cells.

Integrin β6 (N-20) - sc-6633 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ITGB6 antibody - ab197672 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue labeling ITGB6 with ab197672 at 1/10 dilution.

Anti-ITGB6 antibody [EPR15740] - ab187155 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15740
All lanes : Anti-ITGB6 antibody [EPR15740] (ab187155) at 1/10000 dilutionLane 1 : Human fetal skin lysateLane 2 : Human fetal kidney lysateLysates/proteins at 10 µg per lane.SecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-ITGB6 / Integrin Beta 6 Antibody (aa31-992) - LS-C125778 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ITGB6 / Integrin Beta 6 Antibody (clone CSb6) - LS-C24784 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone CSb6

Anti-ITGB6 / Integrin Beta 6 Antibody - LS-C24785 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ITGB6 / Integrin Beta 6 Antibody - LS-C150212 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ITGB6 / Integrin Beta 6 Antibody - LS-C152915 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ITGB6 / Integrin Beta 6 Antibody - LS-C308547 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ITGB6 / Integrin Beta 6 Antibody - LS-C310793 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ITGB6 / Integrin Beta 6 Antibody - LS-C149983 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal
HT-29 human colon adenocarcinoma cells were stained with anti-Integrin beta 6 (grey histogram) or isotype control (open histogram) followed by NorthernLights 557-conjugated anti-sheep antibody.

Anti-ITGB6 / Integrin Beta 6 Antibody (clone 1D2) - LS-C338478 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ITGB6 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ITGB6.

Anti-ITGB6 / Integrin Beta 6 Antibody (clone 4C3) - LS-C197558 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4C3
Detection limit for recombinant GST tagged ITGB6 is approximately 0.03 ng/ml as a capture antibody.

Anti-ITGB6 / Integrin Beta 6 Antibody (aa755-783) - LS-C165328 from LifeSpan Bioscience

Prices $250.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ITGB6 Antibody (C-term) Western blot of K562 cell line lysates (35 ug/lane). This demonstrates the ITGB6 antibody detected the ITGB6 protein (arrow).

Integrin beta 6 Antibody [Unconjugated] - AF4155 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Integrin beta 6 was detected in immersion fixed HT‑29 human colon adenocarcinoma cell line using Sheep Anti-Human Integrin beta 6 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4155) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (red; Catalog # NL010) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm and cell surface. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Integrin beta 6 Antibody (437211) [Unconjugated] - MAB4155 from Novus Biologicals

Prices $99.00, $259.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 437211
Integrin beta 6 was detected in immersion fixed HT‑29 human colon adenocarcinoma cell line using Mouse Anti-Human Integrin beta 6 Monoclonal Antibody (Catalog # MAB4155) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI(blue). Specific staining was localized to cytoplasm and cell surface. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Integrin beta 6 Antibody - NBP2-14136 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Integrin beta 6 Antibody [NBP2-14136] - Staining of human rectum shows strong cytoplasmic and membranous positivity in granular pattern in glandular cells.

Integrin beta 6 Antibody (437216) - MAB41551 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 437216

Integrin beta 6 Antibody (CSbeta6) - NBP2-29800 from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone CSbeta6

Integrin beta 6 Antibody - H00003694-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Integrin beta 6 Antibody - H00003694-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ITGB6 Antibody [H00003694-D01] - Expression in transfected 293T cell line. Lane 1: ITGB6 transfected lysate(85.9 KDa). Lane 2: Non-transfected lysate.

Integrin beta 6 Antibody - H00003694-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Integrin beta 6 Antibody (4C3) - H00003694-M03 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4C3
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