ITGB6

Gene Symbol ITGB6
Entrez Gene 3694
Alt Symbol AI1H
Species Human
Gene Type protein-coding
Description integrin, beta 6
Other Description integrin beta-6
Swissprots P18564 B2R9W5 Q53RG5 Q16500 Q0VA95 Q53RR6 C9JA97
Accessions AAB23690 AAX93093 AAY24053 CAA01832 EAX11390 P18564 AI264144 AK026736 AK290300 BAF82989 AK304203 BAG65080 AK313944 BAG36662 AL359053 AL831998 AM393800 CAL38675 BC121178 AAI21179 BC143656 CD013944 CD013945 CD013946 CD013947 DB222211 M35198 AAA36122 NM_000888 NP_000879 NM_001282353 NP_001269282 NM_001282354 NP_001269283 NM_001282355 NP_001269284 NM_001282388 NP_001269317 NM_001282389 NP_001269318 NM_001282390 NP_001269319
Function Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. {ECO:0000269|PubMed:17545607}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways Focal adhesion, ECM-receptor interaction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

Integrin β6 siRNA (h) - sc-43135 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Integrin β6 shRNA Plasmid (h) - sc-43135-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Integrin β6 shRNA (h) Lentiviral Particles - sc-43135-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Integrin beta 6 RNAi - H00003694-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU009241 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10820 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10820 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ITGB6 siRNA (Human) - CRH2483 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ITGB6 - MBS8225131 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Itgb6 (NM_000888.3) - SHH321449 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ITGB6(NM_000888.3) - SHL183960 from Creative biogene

Category siRNA
Species Reactivities Human

ITGB6 shRNA Plasmid (Human) - CHH2483 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ITGB6 miRNA 3'UTR clone - MiUTR1H-05039 from Creative biogene

Species Reactivities Human
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