ENG

Gene Symbol	ENG
Entrez Gene	2022
Alt Symbol	END, HHT1, ORW1
Species	Human
Gene Type	protein-coding
Description	endoglin
Other Description	CD105 antigen
Swissprots	Q14926 Q14248 P17813 Q5T9C0
Accessions	AAC32802 AAC63386 ABI75346 EAW87702 EAW87703 EAW87704 P17813 AK222669 AK223044 BAD96764 AK290389 BAF83078 AK300156 BAG61940 AK301171 BAH13421 AK302455 BAG63750 BC014271 AAH14271 BC020391 BC031967 BT006872 AAP35518 DA943458 DB079257 DQ893673 ABM84599 DQ895827 ABM86753 J05481 AAA35800 X72012 CAA50891 NM_000118 NP_000109 NM_001114753 NP_001108225 NM_001278138 NP_001265067
Function	Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF- beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3. {ECO:0000269|PubMed:21737454, ECO:0000269|PubMed:23300529}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Endoglin is restricted to endothelial cells in all tissues except bone marrow.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ENG 293T Cell Transient Overexpression Lysate(Denatured) - H00002022-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

ENG 293 Cell Lysate - 410330 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

Endoglin/CD105 Overexpression Lysate (Native) - NBL1-10266 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

Endoglin (h): 293T Lysate - sc-170141 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

ENG Over-expression Lysate Product - GWB-ACF6A0 from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

Human Endoglin / CD105 / ENG HEK293 Cell Lysate (WB positive control) - 10149-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human Endoglin / CD105 / ENG HEK293 Cell Lysate (WB positive control) - 10149-H02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human Endoglin Human Cells Transfected Lysate (positive control) (denatured) - orb172882 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Endoglin/CD105 Overexpression Lysate (Denatured) - H00002022-T01 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Human Endoglin Human Cells Transfected Lysate (positive control) (denatured) - orb173369 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human ENG Knockdown Stable Cell Line - CSC-DC004932 from Creative biogene Category Cell Line Species Human

ENG Knockout Cell Line-HeLa - CSC-RT1779 from Creative biogene Category Cell Line Species Human

ENG KO Cell Lysate-HeLa - CLKO-1628 from Creative biogene Category Cell Lysate

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