ENG

Gene Symbol	ENG
Entrez Gene	2022
Alt Symbol	END, HHT1, ORW1
Species	Human
Gene Type	protein-coding
Description	endoglin
Other Description	CD105 antigen
Swissprots	Q14926 Q14248 P17813 Q5T9C0
Accessions	AAC32802 AAC63386 ABI75346 EAW87702 EAW87703 EAW87704 P17813 AK222669 AK223044 BAD96764 AK290389 BAF83078 AK300156 BAG61940 AK301171 BAH13421 AK302455 BAG63750 BC014271 AAH14271 BC020391 BC031967 BT006872 AAP35518 DA943458 DB079257 DQ893673 ABM84599 DQ895827 ABM86753 J05481 AAA35800 X72012 CAA50891 NM_000118 NP_000109 NM_001114753 NP_001108225 NM_001278138 NP_001265067
Function	Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF- beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3. {ECO:0000269|PubMed:21737454, ECO:0000269|PubMed:23300529}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Endoglin is restricted to endothelial cells in all tissues except bone marrow.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Endoglin CRISPR/Cas9 KO Plasmid (h) - sc-400599 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Endoglin HDR Plasmid (h) - sc-400599-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Endoglin Double Nickase Plasmid (h) - sc-400599-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Endoglin Double Nickase Plasmid (h2) - sc-400599-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Endoglin CRISPR Activation Plasmid (h) - sc-400599-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Endoglin CRISPR Activation Plasmid (h2) - sc-400599-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Endoglin Lentiviral Activation Particles (h) - sc-400599-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Endoglin Lentiviral Activation Particles (h2) - sc-400599-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Endoglin siRNA (h) - sc-35302 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Endoglin shRNA Plasmid (h) - sc-35302-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Endoglin shRNA (h) Lentiviral Particles - sc-35302-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Endoglin/CD105 RNAi - H00002022-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU091861 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7868 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7868 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07253 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr07253

ENG siRNA (Human) - CRH1403 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ENG - MBS8219784 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ENG (NM_000118.2) - SHH285769 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ENG(NM_000118.2) - SHH033623 from Creative biogene Category siRNA Species Reactivities Human

Human ENG siRNA - orb261905 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ENG shRNA Plasmid (Human) - CHH1403 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ENG miRNA 3'UTR clone - MiUTR1H-03225 from Creative biogene Species Reactivities Human

ENG miRNA 3'UTR clone - MiUTR3H-00723 from Creative biogene Species Reactivities Human

Search more