ENG

Gene Symbol	ENG
Entrez Gene	2022
Alt Symbol	END, HHT1, ORW1
Species	Human
Gene Type	protein-coding
Description	endoglin
Other Description	CD105 antigen
Swissprots	Q14926 Q14248 P17813 Q5T9C0
Accessions	AAC32802 AAC63386 ABI75346 EAW87702 EAW87703 EAW87704 P17813 AK222669 AK223044 BAD96764 AK290389 BAF83078 AK300156 BAG61940 AK301171 BAH13421 AK302455 BAG63750 BC014271 AAH14271 BC020391 BC031967 BT006872 AAP35518 DA943458 DB079257 DQ893673 ABM84599 DQ895827 ABM86753 J05481 AAA35800 X72012 CAA50891 NM_000118 NP_000109 NM_001114753 NP_001108225 NM_001278138 NP_001265067
Function	Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF- beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3. {ECO:0000269|PubMed:21737454, ECO:0000269|PubMed:23300529}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Endoglin is restricted to endothelial cells in all tissues except bone marrow.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-ENG-cDNA-Clone - DC03803 from Abgent, a WuXi AppTec company Prices $888.30 Sizes 10 µg Species Human Accession BC014271

ENG - MBS1269451 from MyBioSource Species Human Accession BC014271

Human ENG cDNA clone(NM_001114753.1) - CDFH005917 from Creative Biomart Species Human Accession NM_001114753.1

Human ENG ORF Clone(NM_000118.2) - CDCL162360 from Creative Biomart Species Human Accession NM_000118.2

Human ENG ORF Clone(NM_001114753.1) - CDCR348128 from Creative Biomart Species Human Accession NM_001114753.1

Human ENG ORF Clone(NM_001114753.1) - CDCR348129 from Creative Biomart Species Human Accession NM_001114753.1

Human Endoglin/CD105 transcript variant 1 Gene ORF cDNA clone in cloning vector - HG10149-M from Sino Biological Species Human

Human Endoglin/CD105 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10149-CM from Sino Biological Species Human

Human CD105 / ENG transcript variant 1 Gene cDNA Clone (full-length ORF Clone) expression ready, FLAG-tagged - HG10149-M-F from Sino Biological Species Human Accession NM_001114753.1

Human Endoglin/CD105 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-His tag - HG10149-NH from Sino Biological Species Human

Human Endoglin/CD105 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10149-ACR from Sino Biological Species Human

Human Endoglin/CD105 transcript variant 1 Gene ORF cDNA clone expression plasmid - HG10149-M-N from Sino Biological Species Human

Human CD105 / ENG transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG10149-UT from Sino Biological Species Human Accession NM_001114753.1

Human Endoglin/CD105 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10149-CY from Sino Biological Species Human

Human Endoglin/CD105 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-His tag - HG10149-CH from Sino Biological Species Human

Human CD105 / ENG transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-tagged - HG10149-NF from Sino Biological Species Human Accession NM_001114753.1

Human Endoglin/CD105 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10149-CF from Sino Biological Species Human

Human Endoglin/CD105 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10149-NM from Sino Biological Species Human

Human Endoglin/CD105 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10149-NY from Sino Biological Species Human

Human Endoglin/CD105 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10149-ACG from Sino Biological Species Human

Human CD105 ORF clone(NM_001114753.1) - CDCL183166 from Creative biogene Species Human

Human ENG ORF Clone (BC014271) - CDCS405434 from Creative biogene Species Human Accession P17813

Human ENG cDNA Clone(NM_001114753.1) - CDFH005917 from Creative biogene Species Human

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