FKBP4

Gene Symbol	FKBP4
Entrez Gene	2288
Alt Symbol	FKBP51, FKBP52, FKBP59, HBI, Hsp56, PPIase, p52
Species	Human
Gene Type	protein-coding
Description	FK506 binding protein 4, 59kDa
Other Description	51 kDa FK506-binding protein|FK506-binding protein 4 (59kD)|HSP binding immunophilin|T-cell FK506-binding protein, 59kD|peptidyl-prolyl cis-trans isomerase FKBP4|peptidylprolyl cis-trans isomerase|rotamase
Swissprots	Q9UCP1 D3DUQ1 Q9UCV7 Q02790
Accessions	EAW88889 EAW88890 Q02790 AK024694 AK313918 BAG36639 BC001786 AAH01786 BC002887 BC007924 AAH07924 BQ083177 BQ446607 BU685040 DA392592 DQ893668 ABM84594 DQ895800 ABM86726 M88279 AAA36111 XM_011520929 XP_011519231 NM_002014 NP_002005
Function	Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria. {ECO:0000269|PubMed:1279700, ECO:0000269|PubMed:1376003, ECO:0000269|PubMed:19945390, ECO:0000269|PubMed:21730050, ECO:0000269|PubMed:2378870}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000250}. Mitochondrion. Nucleus. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Shuttles from mitochondria to nucleus; co-localizes in mitochondria with the glucocorticoid receptor.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:1279700}.
Top Pathways	Estrogen signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FKBP4 / FKBP52 ELISA Kit (Sandwich ELISA) - LS-F9517 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.057 ng/ml Range 0.156-10 ng/ml

Human FKBP4 ELISA Kit - abx151562 from Abbexa Category ELISA Kit Sensitivity 0.057 ng/ml Range 0.156 ng/ml - 10 ng/ml

FKBP4 (Human) IP-WB Antibody Pair - H00002288-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

FKBP4 (Human) IP-WB Antibody Pair - H00002288-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

FKBP4 (Human) Matched Antibody Pair - H00002288-AP21 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

FKBP4 (Human) Matched Antibody Pair - H00002288-AP22 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

ELISA Kit for FK506 Binding Protein 4 (FKBP4) - SEE644Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.057ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for FK506 Binding Protein 4 (FKBP4) - SEE644Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.057ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

FK506 Binding Protein 5 (FKBP5), Human, ELISA Kit - DL-FKBP5-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.625-40 ng/mL

NF-kappaB p100/p52 ELISA Kit - DEIA-XYA1318 from Creative Diagnostics Category ELISA Kit

NF-kappaB p100/p52 ELISA Kit - DEIA-XYA1319 from Creative Diagnostics Category ELISA Kit

NF-kappaB p100/p52 (Phospho-Ser865) ELISA Kit - DEIA-XYA1320 from Creative Diagnostics Category ELISA Kit

NF-kappaB p100/p52 (Phospho-Ser865) ELISA Kit - DEIA-XYA1321 from Creative Diagnostics Category ELISA Kit

NF-kappaB p100/p52 (Phospho-Ser869) ELISA Kit - DEIA-XYA1322 from Creative Diagnostics Category ELISA Kit

NF-kappaB p100/p52 (Phospho-Ser872) ELISA Kit - DEIA-XYA1323 from Creative Diagnostics Category ELISA Kit

Human FKBP4 ELISA Kit - abx571851 from Abbexa Category ELISA Kit Sensitivity 0.057 ng/ml Range 0.156 ng/ml - 10 ng/ml

Custom Human FKBP52 ELISA - ELH-FKBP52-1 from RayBiotech Category ELISA Kit Prices $627.00, $1,128.60, $2,508.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Custom Human FKBP51 ELISA Kit - orb384581 from Biorbyt Category ELISA Kit Prices $1,411.00, $2,448.00, $5,321.00 Sizes 96 assays, 192 assays, 480 assays

Human FKBP4 ELISA Kit - E015203 from Biobool Category ELISA Kit Sensitivity Typically less than 0.057ng/mL.

FKBP4 ELISA Kit (Human) (OKCD00439) - OKCD00439 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.059 ng/mL Range 0.156-10 ng/mL

FKBP4 ELISA Kit (Human) (OKDD00269) - OKDD00269 from Aviva Systems Biology Category ELISA Kit Prices $580.00 Sizes 96 wells Sensitivity < 0.057 ng/mL Range 0.156-10 ng/mL

anti-FKBP4 antibody - ARG55319 from Arigo Biolaboratories Category ELISA Kit

anti-FKBP52 antibody [Hi52C] - ARG22264 from Arigo Biolaboratories Category ELISA Kit

anti-NFkB p100/p52 antibody - ARG51015 from Arigo Biolaboratories Category ELISA Kit

anti-FKBP51 antibody [Hi51B] - ARG22263 from Arigo Biolaboratories Category ELISA Kit

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