ATP6AP2

Gene Symbol	ATP6AP2
Entrez Gene	10159
Alt Symbol	APT6M8-9, ATP6IP2, ATP6M8-9, ELDF10, HT028, M8-9, MRXE, MRXSH, MSTP009, PRR, RENR, XMRE, XPDS
Species	Human
Gene Type	protein-coding
Description	ATPase, H+ transporting, lysosomal accessory protein 2
Other Description	ATPase H(+)-transporting lysosomal-interacting protein 2|ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9|ATPase, H+ transporting, lysosomal interacting protein 2|ER-localized type I transmembrane adaptor|N14F|V-ATPase M8.9 subunit|embryonic liver differentiation factor 10|prorenin receptor|renin receptor|renin/prorenin receptor|vacuolar ATP synthase membrane sector-associated protein M8-9|vacuolar proton ATP synthase membrane sector associated protein M8-9
Swissprots	Q8NBP3 Q6T7F5 O75787 Q9UG89 Q9H2P8 Q96FV6 Q8NG15 B7Z9I3 Q5QTQ7 Q96LB5
Accessions	AAL11062 EAW59424 O75787 AF109363 AAQ13511 AF248966 AAG44564 AF291814 AAM47531 AK075382 BAC11582 AK293510 BAH11525 AK296614 BAH12399 AK297007 BAH12473 AK297760 BAH12660 AK314633 AK315948 BAH14319 AL049929 CAB43210 AY038990 AAK83467 AY429341 AAR06910 BC010395 AAH10395 BC084541 AAH84541 Y17975 CAA76984 NM_005765 NP_005756
Function	Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS). {ECO:0000269|PubMed:12045255}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncytiotrophoblast cells in the mature fetal placenta. {ECO:0000269|PubMed:12045255, ECO:0000269|PubMed:15746149}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ATP6AP2 gene - orb91788 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

ATP6AP2 - MBS1266529 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC010395

ATP6AP2 - MBS1272504 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC084541

Human ATP6AP2/ATP6IP2 Gene ORF cDNA clone in cloning vector - HG11244-M from Sino Biological Species Human

Human ATP6AP2/ATP6IP2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11244-CY from Sino Biological Species Human

Human ATP6AP2/ATP6IP2 Gene ORF cDNA clone expression plasmid - HG11244-UT from Sino Biological Species Human

Human ATP6AP2/ATP6IP2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11244-ACR from Sino Biological Species Human

Human ATP6AP2/ATP6IP2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11244-NF from Sino Biological Species Human

Human ATP6AP2/ATP6IP2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11244-NM from Sino Biological Species Human

Human ATP6AP2/ATP6IP2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11244-CF from Sino Biological Species Human

Human ATP6AP2/ATP6IP2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11244-NY from Sino Biological Species Human

Human ATP6AP2/ATP6IP2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11244-CM from Sino Biological Species Human

Human ATP6AP2/ATP6IP2 Gene ORF cDNA clone expression plasmid, N-His tag - HG11244-NH from Sino Biological Species Human

Human ATP6AP2/ATP6IP2 Gene ORF cDNA clone expression plasmid, C-His tag - HG11244-CH from Sino Biological Species Human

Human ATP6AP2 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG11244-M-N from Sino Biological Species Human Accession NM_005765.2

Human ATP6AP2/ATP6IP2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11244-ACG from Sino Biological Species Human

ATP6AP2 - CL01182H01 from Elabscience Species Human Accession NM_005765.2

Human ATP6AP2 ORF clone(NM_005765.2) - CDCL182780 from Creative biogene Species Human

Human ATP6AP2 ORF Clone (BC010395) - CDCS412412 from Creative biogene Species Human Accession O75787

Human ATP6AP2 ORF Clone (BC084541) - CDCS412413 from Creative biogene Species Human Accession O75787

Human ATP6AP2 cDNA Clone(NM_005765.2) - CDFH001473 from Creative biogene Species Human

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