ATP6AP2

Gene Symbol	ATP6AP2
Entrez Gene	10159
Alt Symbol	APT6M8-9, ATP6IP2, ATP6M8-9, ELDF10, HT028, M8-9, MRXE, MRXSH, MSTP009, PRR, RENR, XMRE, XPDS
Species	Human
Gene Type	protein-coding
Description	ATPase, H+ transporting, lysosomal accessory protein 2
Other Description	ATPase H(+)-transporting lysosomal-interacting protein 2|ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9|ATPase, H+ transporting, lysosomal interacting protein 2|ER-localized type I transmembrane adaptor|N14F|V-ATPase M8.9 subunit|embryonic liver differentiation factor 10|prorenin receptor|renin receptor|renin/prorenin receptor|vacuolar ATP synthase membrane sector-associated protein M8-9|vacuolar proton ATP synthase membrane sector associated protein M8-9
Swissprots	Q8NBP3 Q6T7F5 O75787 Q9UG89 Q9H2P8 Q96FV6 Q8NG15 B7Z9I3 Q5QTQ7 Q96LB5
Accessions	AAL11062 EAW59424 O75787 AF109363 AAQ13511 AF248966 AAG44564 AF291814 AAM47531 AK075382 BAC11582 AK293510 BAH11525 AK296614 BAH12399 AK297007 BAH12473 AK297760 BAH12660 AK314633 AK315948 BAH14319 AL049929 CAB43210 AY038990 AAK83467 AY429341 AAR06910 BC010395 AAH10395 BC084541 AAH84541 Y17975 CAA76984 NM_005765 NP_005756
Function	Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS). {ECO:0000269|PubMed:12045255}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncytiotrophoblast cells in the mature fetal placenta. {ECO:0000269|PubMed:12045255, ECO:0000269|PubMed:15746149}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ATP6IP2 full length protein - ab153053 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human ATP6IP2 full length protein - ab109673 from Abcam Category Protein Prices $955.00 Sizes 1 ml Source Native Species Human

Human ATP6IP2 peptide - ab41522 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human ATP6IP2 protein fragment - ab167955 from Abcam Category Protein Prices $577.00 Sizes 100 µg Source E. coli Species Human

ATP6AP2 / Renin Receptor Antibody Blocking Peptide - LS-E25609 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Renin R Protein - H00010159-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Renin R Blocking Peptide - NB100-1318PEP from Novus Biologicals Category Peptide Prices $229.00 Sizes 100 µg

Human ATP6AP2 protein - orb246300 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human ATP6AP2 protein - orb191270 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E. coli Species Human

Human ATP6AP2 Protein - abx065476 from Abbexa Category Protein Source E.coli Species Human

Renin Receptor Blocking Peptide - abx063654 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Chicken, Dog, Pig

ATP6IP2 Peptide - AC21-0440-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Renin receptor - H00010159-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Renin receptor - H00010159-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Renin Receptor Peptide - 46-280P from ProSci Category Peptide Species Human, Mouse, Rat

RENIN-RECEPTOR,ATP6AP2 fusion protein - Ag17725 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

RENIN-RECEPTOR,ATP6AP2 fusion protein - Ag1360 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human ATP6AP2 - ATP6AP2-2443H from Creative Biomart Category Protein Source HEK cells.

Recombinant Human ATP6AP2, His-tagged - ATP6AP2-2444H from Creative Biomart Category Protein Source HEK cells.

Native Human ATP6AP2 - ATP6AP2-27064TH from Creative Biomart Category Protein Species Human

Recombinant ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2) - RPG393Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2) - RPG393Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Renin Receptor Blocking Peptide - CBP2460 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Chicken, Dog, Pig

Renin Receptor Peptide - BS5887P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2) - RPG393Hu01 from Cloud-clone Category Protein Source E.coli Species Human

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