EFNA5

Gene Symbol EFNA5
Entrez Gene 1946
Alt Symbol AF1, EFL5, EPLG7, GLC1M, LERK7, RAGS
Species Human
Gene Type protein-coding
Description ephrin-A5
Other Description AL-1|LERK-7|eph-related receptor tyrosine kinase ligand 7
Swissprots P52803
Accessions EAW49063 EAW49064 EAW49065 P52803 AK025909 AK308672 BC075054 AAH75054 BC075055 AAH75055 U26403 AAB60377 XM_006714565 XP_006714628 XM_011543250 XP_011541552 XM_011543251 XP_011541553 NM_001962 NP_001953
Function Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Induces compartmentalized signaling within a caveolae-like membrane microdomain when bound to the extracellular domain of its cognate receptor. This signaling event requires the activity of the Fyn tyrosine kinase. Activates the EPHA3 receptor to regulate cell-cell adhesion and cytoskeletal organization. With the receptor EPHA2 may regulate lens fiber cells shape and interactions and be important for lens transparency maintenance. May function actively to stimulate axon fascicu
Subcellular Location Cell membrane {ECO:0000269|PubMed:11870224}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:11870224}. Membrane, caveola {ECO:0000269|PubMed:11870224}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:11870224}. Note=Compartmentalized in discrete caveolae-like membrane microdomains.
Top Pathways Axon guidance, PI3K-Akt signaling pathway, Rap1 signaling pathway

ephrin-A5 (C-19) - sc-6075 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ephrin-A5 (H-66) - sc-20722 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ephrin-A5 (H-66): sc-20722. Immunoperoxidase staining of formalin fixed, paraffin-embedded human epididymis tissue showing cytoplasmic and nuclear staining of glandular cells.

ephrin-A5 (N-19) - sc-1951 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ephrin-A5 (RR-7) - sc-81945 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
ephrin-A5 (RR-7): sc-81945. Western blot analysis of ephrin-A5 expression in NIH/3T3 whole cell lysate.

Anti-Ephrin A5 antibody - ab70114 from Abcam

Prices $391.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab70114 staining anti-Ephrin A5 in wild-type and knockout mouse inferior colliculus/cerebellum tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with paraformaldehyde and blocked with 1% BSA for 15 minutes at 20°C; antigen retrieval was by heat mediation with citric acid. Samples were incubated with primary antibody (1/200 in 1 % TBS/BSA buffer) for 2 hours at 20°C. A Biotin-conjugated Goat anti-rabbit IgG polyclonal (1/200) was used as the secondary antibody.See Abreview

Anti-Ephrin A5 antibody - ab51779 from Abcam

Host Chicken
Clonality Polyclonal
Anti-Ephrin A5 antibody (ab51779) at 1/2000 dilution + E coli-derived fusion protein at 15 µgSecondary Goat anti-IgY-HRP dilution: at 1/1000 dilution

Anti-EFNA5 / Ephrin A5 Antibody (Biotin) - LS-C318795 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-EFNA5 / Ephrin A5 Antibody (FITC) - LS-C317120 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-EFNA5 / Ephrin A5 Antibody (aa66-115) - LS-C151976 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
EFNA5 / Ephrin A5 antibody Western Blot of HeLa.

Anti-EFNA5 / Ephrin A5 Antibody (aa84-133) - LS-C151977 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
EFNA5 / Ephrin A5 antibody Western Blot of HeLa.

Anti-EFNA5 / Ephrin A5 Antibody (aa189-200) IHC-plus™ - LS-B5137 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-EFNA5 / Ephrin A5 antibody IHC of human cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5137 concentration 3.75 ug/ml.

Anti-EFNA5 / Ephrin A5 Antibody (aa31-80) IHC-plus™ - LS-B7057 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-EFNA5 / Ephrin A5 antibody IHC of human brain, cortex neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7057 concentration 10 ug/ml.

Anti-EFNA5 / Ephrin A5 Antibody (C-Terminus) - LS-C6543 from LifeSpan Bioscience

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-EFNA5 / Ephrin A5 Antibody (clone 1A2) - LS-C139067 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A2

Anti-EFNA5 / Ephrin A5 Antibody (aa114-204) - LS-C125533 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-EFNA5 / Ephrin A5 Antibody - LS-C285494 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-EFNA5 / Ephrin A5 Antibody (HRP) - LS-C317121 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-EFNA5 / Ephrin A5 Antibody (Pro63) - LS-C177019 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of Ephrin-A5 (P63) pAb in paraffin-embedded human brain tissue.

Ephrin-A5 Antibody [Unconjugated] - AF3743 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Ephrin‑A5 was detected in immersion fixed paraffin-embedded sections of human melanoma using Goat Anti-Human Ephrin‑A5 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3743) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Ephrin-A5 Antibody - NBP1-67969 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Ephrin-A5 Antibody [NBP1-67969] - Analysis of extracts from HeLa cells, using Ephrin- A5 Antibody. The lane on the right is treated with the synthesized peptide.

Ephrin-A5 Antibody - NBP1-19682 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Ephrin A5 Antibody [NBP1-19682] - Western blot analysis of Ephrin-A5 in extracts from HeLa cells.

Ephrin-A5 Antibody (1F12) - H00001946-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F12
Western Blot: Ephrin-A5 Antibody (1F12) [H00001946-M01] - EFNA5 monoclonal antibody (M01), clone 1F12. Analysis of EFNA5 expression in IMR-32.

Ephrin-A5 Antibody - H00001946-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Ephrin A5 Antibody [H00001946-A01] - EFNA5 polyclonal antibody (A01), Lot # 051128JC01 Western Blot analysis of EFNA5 expression in U-2 OS ( Cat # L022V1 ).

Ephrin-A5 Antibody (1A2) - H00001946-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A2

Ephrin-A5 Antibody [Biotin] - BAF3743 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
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