Gene Symbol | QSOX2 |
---|---|
Entrez Gene | 169714 |
Alt Symbol | QSCN6L1, SOXN |
Species | Human |
Gene Type | protein-coding |
Description | quiescin Q6 sulfhydryl oxidase 2 |
Other Description | neuroblastoma-derived sulfhydryl oxidase|quiescin Q6-like 1|quiescin Q6-like protein 1|sulfhydryl oxidase 2 |
Swissprots | Q7Z7B6 Q8N3G2 Q86VV7 Q6ZRP7 Q5TB37 A6NLB0 A2CEE0 |
Accessions | EAW88207 EAW88208 EAW88209 Q6ZRP7 AJ318051 CAC85331 AJ420461 AK128077 BAC87262 AK128750 BAG54726 AL834369 CAD39032 BC047604 AAH47604 BQ269870 DQ575499 NM_181701 NP_859052 |
Function | Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. Also seems to play a role in regulating the sensitization of neuroblastoma cells for interferon-gamma-induced apoptosis. {ECO:0000269|PubMed:14633699}. |
Subcellular Location | Membrane {ECO:0000269|PubMed:14633699}; Single-pass membrane protein {ECO:0000269|PubMed:14633699}. Secreted {ECO:0000269|PubMed:14633699}. Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Nucleus membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=Seems to be predominantly targeted to the nuclear and outer plasma membrane. |
Tissue Specificity | Expressed in pancreas, brain, placenta, kidney, heart and fetal tissues. Weakly expressed in lung, liver and skeletal muscles. {ECO:0000269|PubMed:14633699}. |
SOXN (G-20) - sc-139427 from Santa Cruz Biotechnology
|
||||||||
SOXN (K-19) - sc-139428 from Santa Cruz Biotechnology
|
||||||||
Anti-QSOX2 antibody - ab121376 from Abcam
|
||||||||
Anti-QSOX2 antibody - C-terminal - ab191168 from Abcam
|
||||||||
Anti-QSOX2 Antibody (Internal) IHC-plus⢠- LS-A9142 from LifeSpan Bioscience
|
||||||||
Anti-QSOX2 Antibody (aa542-591) - LS-C186829 from LifeSpan Bioscience
|
||||||||
Anti-QSOX2 Antibody (Internal) IHC-plus⢠- LS-A9144 from LifeSpan Bioscience
|
||||||||
Anti-QSOX2 Antibody (C-Terminus) IHC-plus⢠- LS-A9859 from LifeSpan Bioscience
|
||||||||
Anti-QSOX2 Antibody (Internal) IHC-plus⢠- LS-A9858 from LifeSpan Bioscience
|
||||||||
QSOX2 Antibody - NBP1-84094 from Novus Biologicals
|
||||||||
Anti-QSOX2 antibody produced in rabbit - HPA012716 from Sigma-Aldrich
|
||||||||
Anti-QSOX2 antibody produced in rabbit - SAB2900729 from Sigma-Aldrich
|
||||||||
Anti-QSOX2 antibody produced in rabbit - SAB2900730 from Sigma-Aldrich
|
||||||||
Anti-QSOX2 antibody produced in rabbit - SAB2900682 from Sigma-Aldrich
|
||||||||
QSOX2 Antibody - middle region (ARP67254_P050) - ARP67254_P050 from Aviva Systems Biology
|
||||||||
QSOX2 Antibody (OALA01464) - OALA01464 from Aviva Systems Biology
|
||||||||
QSOX2 Antibody (OALA01465) - OALA01465 from Aviva Systems Biology
|
||||||||
QSOX2 Antibody (OALA01689) - OALA01689 from Aviva Systems Biology
|
||||||||
QSOX2 Antibody (OALA01690) - OALA01690 from Aviva Systems Biology
|
||||||||
Rabbit Anti-Human QSOX2 (Internal) - 119-12827 from RayBiotech
|
||||||||
Rabbit Anti-Human QSOX2 (C-Terminus) - 119-12828 from RayBiotech
|
||||||||
Rabbit Anti-Human QSOX2 (Internal) - 119-17549 from RayBiotech
|
||||||||
Rabbit Anti-Human QSOX2 (Internal) - 119-17550 from RayBiotech
|
||||||||
QSOX2 Antibody - 71-107 from ProSci
|
||||||||
QSOX2 Antibody - 71-108 from ProSci
|