Gene Symbol | QSOX2 |
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Entrez Gene | 169714 |
Alt Symbol | QSCN6L1, SOXN |
Species | Human |
Gene Type | protein-coding |
Description | quiescin Q6 sulfhydryl oxidase 2 |
Other Description | neuroblastoma-derived sulfhydryl oxidase|quiescin Q6-like 1|quiescin Q6-like protein 1|sulfhydryl oxidase 2 |
Swissprots | Q7Z7B6 Q8N3G2 Q86VV7 Q6ZRP7 Q5TB37 A6NLB0 A2CEE0 |
Accessions | EAW88207 EAW88208 EAW88209 Q6ZRP7 AJ318051 CAC85331 AJ420461 AK128077 BAC87262 AK128750 BAG54726 AL834369 CAD39032 BC047604 AAH47604 BQ269870 DQ575499 NM_181701 NP_859052 |
Function | Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. Also seems to play a role in regulating the sensitization of neuroblastoma cells for interferon-gamma-induced apoptosis. {ECO:0000269|PubMed:14633699}. |
Subcellular Location | Membrane {ECO:0000269|PubMed:14633699}; Single-pass membrane protein {ECO:0000269|PubMed:14633699}. Secreted {ECO:0000269|PubMed:14633699}. Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Nucleus membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=Seems to be predominantly targeted to the nuclear and outer plasma membrane. |
Tissue Specificity | Expressed in pancreas, brain, placenta, kidney, heart and fetal tissues. Weakly expressed in lung, liver and skeletal muscles. {ECO:0000269|PubMed:14633699}. |
QSOX2 Antibody Blocking Peptide - LS-E29567 from LifeSpan Bioscience
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QSOX2 Antibody Blocking Peptide - LS-E29566 from LifeSpan Bioscience
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QSOX2 Antibody Blocking Peptide - LS-E24360 from LifeSpan Bioscience
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QSOX2 Antibody Blocking Peptide - LS-E29792 from LifeSpan Bioscience
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QSOX2 Antibody Blocking Peptide - LS-E29793 from LifeSpan Bioscience
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QSOX2-Antibody-Center-Blocking-peptide - BP13657c from Abgent, a WuXi AppTec company
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Recombinant Human QSOX2 - QSOX2-1160H from Creative Biomart
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QSOX2 Recombinant Protein Antigen - NBP1-84094PEP from Novus Biologicals
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QSOX2 Peptide, Human - M34GP12804H from Creative Peptides
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QSOX2 Recombinant Protein Antigen - NBP2-55031PEP from Novus Biologicals
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Sulfhydryl oxidase 2 (QSOX2), Recombinant Protein - MBS7089568 from MyBioSource
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Sulfhydryl oxidase 2 (QSOX2), Recombinant Protein - MBS7028404 from MyBioSource
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Recombinant Human QSOX2 protein, GST-tagged - QSOX2-12H from Creative Biomart
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