Gene Symbol | GPR31 |
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Entrez Gene | 2853 |
Alt Symbol | 12-HETER, HETER, HETER1 |
Species | Human |
Gene Type | protein-coding |
Description | G protein-coupled receptor 31 |
Other Description | 12-(S)-HETE acid receptor|12-(S)-HETE receptor|12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (HETE) receptor|12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor|G-protein coupled receptor 31|bA517H2.2 (G protein-coupled receptor 31)|hydroxyeicosatetraenoic (HETE) acid receptor 1|probable G-protein coupled receptor 31 |
Swissprots | Q9NQ20 B0M0K2 Q4VBL3 O00270 |
Accessions | AAC51375 ABY87916 EAW47505 O00270 BC095537 AAH95537 BC167778 AAI67778 CD246167 NM_005299 NP_005290 |
Function | High-affinity receptor for 12-(S)-hydroxy-5,8,10,14- eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B. {ECO:0000269|PubMed:21712392}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:21712392}; Multi-pass membrane protein {ECO:0000269|PubMed:21712392}. |
GPR31 (C-17) - sc-103520 from Santa Cruz Biotechnology
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Anti-GPCR GPR31 antibody - ab75579 from Abcam
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Anti-GPCR GPR31 antibody - Extracellular domain - ab150633 from Abcam
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Anti-GPR31 Antibody (N-Terminus) IHC-plus⢠- LS-B9792 from LifeSpan Bioscience
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Anti-GPR31 Antibody (Extracellular Domain) IHC-plus⢠- LS-A1158 from LifeSpan Bioscience
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Anti-GPR31 Antibody - LS-C186429 from LifeSpan Bioscience
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Anti-GPR31 Antibody (aa181-230) - LS-C120715 from LifeSpan Bioscience
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Anti-GPR31 Antibody (aa205-254) - LS-C205857 from LifeSpan Bioscience
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GPR31 Antibody - NBP1-87468 from Novus Biologicals
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GPR31 Antibody - NBP1-87540 from Novus Biologicals
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GPR31 Antibody - NLS1160 from Novus Biologicals
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GPR31 Polyclonal Antibody - bs-13530R from Bioss
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Rabbit Anti-GPR31 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13530R-A350 from Bioss
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Rabbit Anti-GPR31 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13530R-A488 from Bioss
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Rabbit Anti-GPR31 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13530R-A555 from Bioss
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Rabbit Anti-GPR31 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13530R-A647 from Bioss
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Rabbit Anti-GPR31 Polyclonal Antibody, Cy3 Conjugated - bs-13530R-Cy3 from Bioss
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Rabbit Anti-GPR31 Polyclonal Antibody, Cy5 Conjugated - bs-13530R-Cy5 from Bioss
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Rabbit Anti-GPR31 Polyclonal Antibody, Cy5.5 Conjugated - bs-13530R-Cy5.5 from Bioss
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Rabbit Anti-GPR31 Polyclonal Antibody, Cy7 Conjugated - bs-13530R-Cy7 from Bioss
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Rabbit Anti-GPR31 Polyclonal Antibody, FITC Conjugated - bs-13530R-FITC from Bioss
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Rabbit Anti-GPR31 Polyclonal Antibody, Biotin Conjugated - bs-13530R-Biotin from Bioss
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Rabbit Anti-GPR31 Polyclonal Antibody, HRP Conjugated - bs-13530R-HRP from Bioss
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Anti-GPR31 antibody produced in rabbit - HPA014014 from Sigma-Aldrich
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Anti-GPR31 antibody produced in rabbit - HPA027108 from Sigma-Aldrich
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