Gene Symbol | GPR31 |
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Entrez Gene | 2853 |
Alt Symbol | 12-HETER, HETER, HETER1 |
Species | Human |
Gene Type | protein-coding |
Description | G protein-coupled receptor 31 |
Other Description | 12-(S)-HETE acid receptor|12-(S)-HETE receptor|12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (HETE) receptor|12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor|G-protein coupled receptor 31|bA517H2.2 (G protein-coupled receptor 31)|hydroxyeicosatetraenoic (HETE) acid receptor 1|probable G-protein coupled receptor 31 |
Swissprots | Q9NQ20 B0M0K2 Q4VBL3 O00270 |
Accessions | AAC51375 ABY87916 EAW47505 O00270 BC095537 AAH95537 BC167778 AAI67778 CD246167 NM_005299 NP_005290 |
Function | High-affinity receptor for 12-(S)-hydroxy-5,8,10,14- eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B. {ECO:0000269|PubMed:21712392}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:21712392}; Multi-pass membrane protein {ECO:0000269|PubMed:21712392}. |
Human GPCR GPR31 full length protein - ab158567 from Abcam
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GPR31 Antibody Blocking Peptide - LS-E28157 from LifeSpan Bioscience
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Recombinant Human GPR31 Protein - H00002853-P01 from Novus Biologicals
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GPR31 - H00002853-G01 from Acris Antibodies
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GPR31 - H00002853-P01-10 from Acris Antibodies
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GPR31 - H00002853-P01-25 from Acris Antibodies
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Recombinant Human GPR31 Protein - H00002853-G01 from Novus Biologicals
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12- (S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor (GPR31), Recombinant Protein - MBS1034650 from MyBioSource
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GPR31 Recombinant Protein Antigen - NBP1-87540PEP from Novus Biologicals
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GPR31 Recombinant Protein Antigen - NBP1-87468PEP from Novus Biologicals
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GPR31 Peptide, Human - M34GP06567H from Creative Peptides
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12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor (GPR31), Recombinant Protein - MBS7016187 from MyBioSource
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