SFTPD

Gene Symbol SFTPD
Entrez Gene 6441
Alt Symbol COLEC7, PSP-D, SFTP4, SP-D
Species Human
Gene Type protein-coding
Description surfactant protein D
Other Description collectin 7|collectin-7|lung surfactant protein D|pulmonary surfactant apoprotein|pulmonary surfactant-associated protein D|surfactant, pulmonary-associated protein D|surfactant-associated protein, pulmonary 4
Swissprots Q5T0M3 P35247 Q9UCJ3 Q9UCJ2 Q6FH08 Q8TCD8 Q86YK9
Accessions AAB59450 AAO22991 AEQ16458 EAW80419 EAW80420 EAW80421 P35247 BC022318 AAH22318 BI820265 BM985387 CR541948 CAG46746 X65018 CAA46152 XM_011540087 XP_011538389 XM_011540088 XP_011538390 NM_003019 NP_003010
Function Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. {ECO:0000269|PubMed:23478426}.
Subcellular Location Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.
Tissue Specificity Expressed in lung, brain, pancreas and adipose tissue (mainly mature adipocytes). {ECO:0000269|PubMed:23478426}.
Top Pathways Phagosome

SP-D (1A10A9) - sc-53138 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SP-D (1A10A9): sc-53138. Western blot analysis of human recombinant SP-D fusion protein. Data kindly provided by the Whitsett laboratory, Cincinnati Children's Hospital Medical Center.

SP-D (C-6) - sc-25324 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SP-D (C-6): sc-25324. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lung tissue showing cytoplasmic staining of alveolar cells and macrophages at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

SP-D (C-18) - sc-7708 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SP-D (H-120) - sc-13980 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SP-D (H-120): sc-13980. Western blot analysis of SP-D expression in non-transfected: sc-117752 (A) and mouse SP-D transfected: sc-123722 (B) 293T whole cell lysates.

SP-D (N-14) - sc-7709 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SP-D (N-14): sc-7709. Western blot analysis of SP-D expression in rat lung extract.

SP-D (IIE11) - sc-59698 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/500 µl
Host Mouse
Clonality Monoclonal

SP-D (10H11) - sc-33730 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
SP-D (10H11): sc-33730. Western blot analysis of SP-D expression in human lung tissue extract.

SP-D (245-01) - sc-59695 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
SP-D (245-01): sc-59695. Western blot analysis of SP-D expression in non-transfected: sc-117752 (A) and mouse SP-D transfected: sc-123722 (B) 293T whole cell lysates.

SP-D (IVG8) - sc-52731 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-Surfactant protein D [10B2] antibody (Biotin) - ab191991 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 10B2

Anti-Surfactant protein D antibody - ab101703 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-Surfactant protein D antibody - ab97849 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Surfactant protein D antibody (ab97849) at 1 µg/ml + Fetal thymus cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Surfactant protein D antibody [10B2] - ab26267 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 10B2

Anti-Surfactant protein D antibody [12G5] - ab17781 from Abcam

Prices $394.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 12G5
ab17781 staining Surfactant protein D in human gall bladder tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde, permeabilized with 0.2% Triton X-100 in PBS and blocked with 5% milk for 30 minutes at room temperature; antigen retrieval was by heat mediation in Tris pH 9.0. Samples were incubated with primary antibody (1/500 in PBS) for 16 hours at 4°C. An Alexa Fluor® 594-conjugated goat anti-mouse IgG polyclonal (1/500) was used as the secondary antibody. Counterstained with DAPI.See Abreview

Anti-Surfactant protein D antibody [EP9191] - ab168366 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP9191
All lanes : Anti-Surfactant protein D antibody [EP9191] (ab168366) at 1/1000 dilutionLane 1 : Human fetal lung lysateLane 2 : mouse lung lysateLane 3 : rat lung lysateLane 4 : A549 lysateLane 5 : A375 lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-Surfactant protein D antibody [IIE11] (Biotin) - ab15695 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone IIE11

Anti-Surfactant protein D antibody [SPDE] - ab15687 from Abcam

Prices $370.00
Sizes 125 µg
Host Mouse
Clonality Monoclonal
Clone SPDE

Anti-Surfactant protein D antibody [VI F11] - ab15688 from Abcam

Prices $373.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone VI F11

Anti-Surfactant protein D antibody [VIF11] (Biotin) - ab15696 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone VIF11
ab15696 at a 1/200 dilution staining Surfactant protein D from mouse lung tissue sections by Immunohistochemistry (frozen sections). The antibody was incubated with the tissue for 24 hours and then detected using an Alexa Fluor® 488 conjugated Goat anti-mouse IgG antibody. This image is courtesy of an Abreview submitted by an anonymous researcher on 24 January 2006. See Abreview

Anti-SFTPD / Surfactant Protein D Antibody (clone 2Q2261) - LS-C17964 from LifeSpan Bioscience

Prices $605.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 2Q2261

Anti-SFTPD / Surfactant Protein D Antibody - LS-C17966 from LifeSpan Bioscience

Prices $635.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-SFTPD / Surfactant Protein D Antibody - LS-C17968 from LifeSpan Bioscience

Prices $635.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-SFTPD / Surfactant Protein D Antibody - LS-C17970 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-SFTPD / Surfactant Protein D Antibody - LS-C17967 from LifeSpan Bioscience

Prices $635.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-SFTPD / Surfactant Protein D Antibody - LS-C17969 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
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