Gene Symbol | SRXN1 |
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Entrez Gene | 140809 |
Alt Symbol | C20orf139, Npn3, SRX, SRX1 |
Species | Human |
Gene Type | protein-coding |
Description | sulfiredoxin 1 |
Other Description | sulfiredoxin-1 |
Swissprots | Q8NDM3 B2R543 Q9BYN0 Q96AK6 |
Accessions | Q9BYN0 AF075053 AK098418 BAC05302 AK127435 AK312054 BAG34990 AL833944 CAD38799 AM393140 CAL38018 AM393844 CAL38719 AY427953 AAR87853 BC017001 AAH17001 BC032604 AAH32604 BC047707 AAH47707 BU170568 NM_080725 NP_542763 |
Function | Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. {ECO:0000269|PubMed:15448164, ECO:0000269|PubMed:15590625}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15448164}. |
Tissue Specificity | Widely expressed with highest levels in kidney, lung, spleen and thymus. {ECO:0000269|PubMed:15448164}. |
Sulfiredoxin (B-4) - sc-373829 from Santa Cruz Biotechnology
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Sulfiredoxin (C-17) - sc-51208 from Santa Cruz Biotechnology
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Sulfiredoxin (FL-137) - sc-99076 from Santa Cruz Biotechnology
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Sulfiredoxin (E-7) - sc-166566 from Santa Cruz Biotechnology
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Sulfiredoxin (P-16) - sc-51209 from Santa Cruz Biotechnology
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Sulfiredoxin (E-2) - sc-166747 from Santa Cruz Biotechnology
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Sulfiredoxin (S-17) - sc-51210 from Santa Cruz Biotechnology
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Sulfiredoxin (B-10) - sc-166786 from Santa Cruz Biotechnology
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Sulfiredoxin (Y-15) - sc-51211 from Santa Cruz Biotechnology
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Anti-SRXN1 antibody - ab92298 from Abcam
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Anti-SRXN1 Antibody (Internal) - LS-C112651 from LifeSpan Bioscience
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SRXN1 Antibody - NBP2-14614 from Novus Biologicals
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SRXN1 Antibody - NBP1-36991 from Novus Biologicals
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SRXN1 Polyclonal Antibody - bs-8329R from Bioss
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SRX1-Antibody-internal-region - AF2859a from Abgent, a WuXi AppTec company
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SRXN1 Antibody (OABF01854) - OABF01854 from Aviva Systems Biology
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SRXN1 Antibody (OAEB01863) - OAEB01863 from Aviva Systems Biology
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SRX1 antibody - 70R-21709 from Fitzgerald
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SRXN1 Antibody - abx116966 from Abbexa
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Sulfiredoxin-1 antibody - 14273-1-AP from Acris Antibodies
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Sulfiredoxin-1 antibody - AP16941PU-N from Acris Antibodies
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Anti-SRXN1 Antibody - AC21-1733 from Abcore
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Anti-SRXN1 Antibody (AMCA) - AC21-1733-01 from Abcore
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Anti-SRXN1 Antibody (AP) - AC21-1733-02 from Abcore
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Anti-SRXN1 Antibody (APC) - AC21-1733-03 from Abcore
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