Gene Symbol | SRXN1 |
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Entrez Gene | 140809 |
Alt Symbol | C20orf139, Npn3, SRX, SRX1 |
Species | Human |
Gene Type | protein-coding |
Description | sulfiredoxin 1 |
Other Description | sulfiredoxin-1 |
Swissprots | Q8NDM3 B2R543 Q9BYN0 Q96AK6 |
Accessions | Q9BYN0 AF075053 AK098418 BAC05302 AK127435 AK312054 BAG34990 AL833944 CAD38799 AM393140 CAL38018 AM393844 CAL38719 AY427953 AAR87853 BC017001 AAH17001 BC032604 AAH32604 BC047707 AAH47707 BU170568 NM_080725 NP_542763 |
Function | Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. {ECO:0000269|PubMed:15448164, ECO:0000269|PubMed:15590625}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15448164}. |
Tissue Specificity | Widely expressed with highest levels in kidney, lung, spleen and thymus. {ECO:0000269|PubMed:15448164}. |
SRXN1 Antibody Blocking Peptide - LS-E26901 from LifeSpan Bioscience
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SRX1 blocking peptide - GTX47573-PEP from GeneTex
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SRXN1 Peptide - AC21-1733-P from Abcore
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SRXN1 Peptide - 42-048P from ProSci
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SRX1 fusion protein - Ag5613 from Proteintech Group
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SRX1 fusion protein - ag6172 from Proteintech Group
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Recombinant Human SRX1, GST-tagged - SRX1-2962H from Creative Biomart
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Recombinant Human Sulfiredoxin-1(SRXN1) - CSB-YP887163HU CSB-EP887163HU CSB-BP887163HU CSB-MP887163HU from Cusabio
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SRX1, Peptide - MBS426826 from MyBioSource
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SRXN1 Peptide, Human - M34GP15188H from Creative Peptides
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Sulfiredoxin-1 (SRXN1), Recombinant Protein - MBS1279909 from MyBioSource
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