Gene Symbol | MACC1 |
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Entrez Gene | 346389 |
Alt Symbol | 7A5, SH3BP4L |
Species | Human |
Gene Type | protein-coding |
Description | metastasis associated in colon cancer 1 |
Other Description | SH3 domain-containing protein 7a5|metastasis-associated in colon cancer protein 1|putative binding protein 7a5 |
Swissprots | B2RNR9 Q6ZN28 Q7Z5A5 Q6ZQN8 A8MUS5 |
Accessions | EAL24276 EAW93719 Q6ZN28 AF086401 AJ313524 CAC86408 AK128850 BAC87646 AK131400 BAD18547 AL359055 BC137090 AAI37091 BC144470 CB240872 NM_182762 NP_877439 |
Function | Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo. {ECO:0000269|PubMed:19098908}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:19098908}. Nucleus {ECO:0000269|PubMed:19098908}. Note=Mainly found in the cytoplasm in non-metastasizing tumors. |
Tissue Specificity | Preferentially expressed in metastasizing tumors. {ECO:0000269|PubMed:19098908}. |
MACC1 Antibody Blocking Peptide - LS-E30713 from LifeSpan Bioscience
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MACC1 Peptide - GTX85281-PEP from GeneTex
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Human MACC1 Protein - abx068004 from Abbexa
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MACC1 Control Peptide - AP30528CP-N from Acris Antibodies
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Metastasis Associated In Colon Cancer 1 (MACC1), Human - 20-9535 from ARP American Research Products
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MACC1 Peptide - 5197P from ProSci
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MACC1 fusion protein - Ag17445 from Proteintech Group
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MACC1 fusion protein - ag16884 from Proteintech Group
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Recombinant Human MACC1, His-tagged - MACC1-680H from Creative Biomart
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Recombinant Metastasis Associated In Colon Cancer 1 (MACC1) - RPM667Hu01 from Uscn Life Science Inc.
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MACC1 Blocking Peptide - CBP4066 from Cohesion Biosciences
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Recombinant Metastasis Associated In Colon Cancer 1 (MACC1) - RPM667Hu01 from Cloud-clone
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Recombinant Human Metastasis-associated in colon cancer protein 1(MACC1) ,partial - CSB-YP761627HU CSB-EP761627HU CSB-BP761627HU CSB-MP761627HU from Cusabio
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Metastasis Associated In Colon Cancer 1 (MACC1) - RPU142748 from Biomatik
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MACC1 - TP324774 from Acris Antibodies
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MACC1 Protein - NBP1-89353PEP from Novus Biologicals
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MACC1 Recombinant Protein Antigen - NBP1-89352PEP from Novus Biologicals
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MACC1 Protein - NBP1-89351PEP from Novus Biologicals
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MACC1 Blocking Peptide - abx162559 from Abbexa
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MACC1 Peptide, Human - M34GP09058H from Creative Peptides
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Recombinant Metastasis Associated In Colon Cancer 1 (MACC1) - RPU42748 from Biomatik
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MACC1 Recombinant Protein (OPCD05087) - OPCD05087 from Aviva Systems Biology
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Metastasis Associated In Colon Cancer 1 (MACC1), Recombinant Protein - MBS2010192 from MyBioSource
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Metastasis-associated in colon cancer protein 1 (MACC1), partial, Recombinant Protein - MBS1413666 from MyBioSource
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MACC1 peptide - orb256953 from Biorbyt
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