Gene Symbol | MACC1 |
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Entrez Gene | 346389 |
Alt Symbol | 7A5, SH3BP4L |
Species | Human |
Gene Type | protein-coding |
Description | metastasis associated in colon cancer 1 |
Other Description | SH3 domain-containing protein 7a5|metastasis-associated in colon cancer protein 1|putative binding protein 7a5 |
Swissprots | B2RNR9 Q6ZN28 Q7Z5A5 Q6ZQN8 A8MUS5 |
Accessions | EAL24276 EAW93719 Q6ZN28 AF086401 AJ313524 CAC86408 AK128850 BAC87646 AK131400 BAD18547 AL359055 BC137090 AAI37091 BC144470 CB240872 NM_182762 NP_877439 |
Function | Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo. {ECO:0000269|PubMed:19098908}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:19098908}. Nucleus {ECO:0000269|PubMed:19098908}. Note=Mainly found in the cytoplasm in non-metastasizing tumors. |
Tissue Specificity | Preferentially expressed in metastasizing tumors. {ECO:0000269|PubMed:19098908}. |
MACC1 (D-15) - sc-163595 from Santa Cruz Biotechnology
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MACC1 (H-86) - sc-368497 from Santa Cruz Biotechnology
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MACC1 (V-12) - sc-163596 from Santa Cruz Biotechnology
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Anti-MACC1 antibody - ab106579 from Abcam
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Anti-MACC1 antibody - ab106005 from Abcam
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Anti-MACC1 Antibody (Internal) IHC-plus™ - LS-B5003 from LifeSpan Bioscience
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Anti-MACC1 Antibody (aa522-784, Biotin) - LS-C297395 from LifeSpan Bioscience
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Anti-MACC1 Antibody (aa522-784, FITC) - LS-C304998 from LifeSpan Bioscience
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Anti-MACC1 Antibody (aa522-784) - LS-C295362 from LifeSpan Bioscience
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MACC1 Antibody - NBP1-77968 from Novus Biologicals
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MACC1 Antibody - NBP1-89352 from Novus Biologicals
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MACC1 Antibody - NBP1-89353 from Novus Biologicals
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MACC1 Antibody - NBP1-89351 from Novus Biologicals
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MACC1 Polyclonal Antibody - bs-4293R from Bioss
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Anti-MACC1 antibody produced in rabbit - HPA020103 from Sigma-Aldrich
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Anti-MACC1 antibody produced in rabbit - HPA020081 from Sigma-Aldrich
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Anti-MACC1 antibody produced in rabbit - HPA029476 from Sigma-Aldrich
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Anti-MACC1 antibody produced in rabbit - SAB3500273 from Sigma-Aldrich
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Monoclonal Anti-MACC1 antibody produced in mouse - AMAB90832 from Sigma-Aldrich
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MACC1 antibody - GTX85281 from GeneTex
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MACC1 antibody - orb75211 from Biorbyt
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MACC1 Antibody (OAAF08148) - OAAF08148 from Aviva Systems Biology
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MACC1 Antibody (OABF01439) - OABF01439 from Aviva Systems Biology
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Anti -MACC1 (MACC1 (IN), Metastasis associated in colon cancer 1, SH3 domain-containingprotein 7a5) - 168343 from USBiological Life Science
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Anti -MACC1 (Metastasis-associated in Colon Cancer Protein 1, SH3 Domain-containingProtein 7a5) - M1100-70 from USBiological Life Science
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