ING4

Gene Symbol ING4
Entrez Gene 51147
Alt Symbol my036, p29ING4
Species Human
Gene Type protein-coding
Description inhibitor of growth family, member 4
Other Description brain my036 protein|candidate tumor suppressor p33 ING1 homolog|inhibitor of growth protein 4
Swissprots A4KYM6 Q9UNL4 Q9H3J0 A4KYM4 Q0EF63 Q4VBQ6 D3DUR8 Q96E15 Q0EF62
Accessions EAW88762 EAW88763 EAW88764 EAW88765 EAW88766 EAW88767 EAW88768 EAW88769 EAW88770 EAW88771 EAW88772 EAW88773 Q9UNL4 AB197695 BAF30477 AB197696 BAF30478 AB197697 BAF30479 AF063594 AAG43153 AF110645 AAD48585 AF156552 AAL79773 AK293169 BAG56713 AK303354 BAG64415 AK313621 AW515338 AW614868 BC007781 AAH07781 BC013038 AAH13038 BC095434 AAH95434 BG705367 BG718170 BM727982 BM922497 BP303219 BQ066994 EF152349 ABO61139 EF152350 ABO61140 EF152351 ABO61141 EF152352 ABO61142 JF432448 ADZ15665 XM_005253698 XP_005253755 XM_011520964 XP_011519266 XM_011520965 XP_011519267 XR_242982 XR_242983 NM_001127582 NP_001121054 NM_001127583 NP_001121055 NM_001127584 NP_001121056 NM_001127585 NP_001121057 NM_001127586 NP_001121058 NM_016162 NP_057246 NM_198287
Function Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). {ECO:0000269|PubMed:12750254, ECO:0000269|PubMed:15029197, ECO:0000269|PubMed:15251430, ECO:0000269|PubMed:15528276, ECO:0000269|PubMed:15897452, ECO:0000269|PubMed:16387653}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15029197, ECO:0000269|PubMed:16973615}.

ING4-Over-expression-Lysate - LY13674a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag ING4 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ING4 gene

ING4 293T Cell Transient Overexpression Lysate(Denatured) - H00051147-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

ING4 overexpression lysate - LY426813 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

ING4 293 Cell Lysate - 402199 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

ING4 Overexpression Lysate (Denatured) - H00051147-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
Lane 1: ING4 transfected lysate (28.5 KDa) Lane 2: Non-transfected lysate.

ING4 Overexpression Lysate (Native) - NBL1-11992 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: ING4 Overexpression Lysate (Adult Normal) [NBL1-11992] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ING4.

ING4 (h): 293T Lysate - sc-111547 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

ING4 Over-expression Lysate Product - GWB-C03D80 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

ING4 Overexpression Lysate (Denatured) - H00051147-T02 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Panoply™ Human ING4 Knockdown Stable Cell Line - CSC-DC007645 from Creative biogene

Category Cell Line
Species Human
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