ING4

Gene Symbol	ING4
Entrez Gene	51147
Alt Symbol	my036, p29ING4
Species	Human
Gene Type	protein-coding
Description	inhibitor of growth family, member 4
Other Description	brain my036 protein|candidate tumor suppressor p33 ING1 homolog|inhibitor of growth protein 4
Swissprots	A4KYM6 Q9UNL4 Q9H3J0 A4KYM4 Q0EF63 Q4VBQ6 D3DUR8 Q96E15 Q0EF62
Accessions	EAW88762 EAW88763 EAW88764 EAW88765 EAW88766 EAW88767 EAW88768 EAW88769 EAW88770 EAW88771 EAW88772 EAW88773 Q9UNL4 AB197695 BAF30477 AB197696 BAF30478 AB197697 BAF30479 AF063594 AAG43153 AF110645 AAD48585 AF156552 AAL79773 AK293169 BAG56713 AK303354 BAG64415 AK313621 AW515338 AW614868 BC007781 AAH07781 BC013038 AAH13038 BC095434 AAH95434 BG705367 BG718170 BM727982 BM922497 BP303219 BQ066994 EF152349 ABO61139 EF152350 ABO61140 EF152351 ABO61141 EF152352 ABO61142 JF432448 ADZ15665 XM_005253698 XP_005253755 XM_011520964 XP_011519266 XM_011520965 XP_011519267 XR_242982 XR_242983 NM_001127582 NP_001121054 NM_001127583 NP_001121055 NM_001127584 NP_001121056 NM_001127585 NP_001121057 NM_001127586 NP_001121058 NM_016162 NP_057246 NM_198287
Function	Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). {ECO:0000269|PubMed:12750254, ECO:0000269|PubMed:15029197, ECO:0000269|PubMed:15251430, ECO:0000269|PubMed:15528276, ECO:0000269|PubMed:15897452, ECO:0000269|PubMed:16387653}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:15029197, ECO:0000269|PubMed:16973615}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-ING4-cDNA-Clone - DC02253 from Abgent, a WuXi AppTec company Prices $336.15 Sizes 10 µg Species Human Accession BC007781

ING4 - MBS1268303 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC007781

Human ING4 cDNA clone(NM_001127582.1) - CDFH009252 from Creative Biomart Species Human Accession NM_001127582.1

Human ING4 cDNA clone(NM_001127583.1) - CDFH009253 from Creative Biomart Species Human Accession NM_001127583.1

Human ING4 cDNA clone(NM_001127584.1) - CDFH009254 from Creative Biomart Species Human Accession NM_001127584.1

Human ING4 cDNA clone(NM_001127585.1) - CDFH009255 from Creative Biomart Species Human Accession NM_001127585.1

Human ING4 cDNA clone(NM_001127586.1) - CDFH009256 from Creative Biomart Species Human Accession NM_001127586.1

Human ING4 ORF Clone(NM_016162.3) - CDCL167248 from Creative Biomart Species Human Accession NM_016162.3

Human ING4 ORF Clone(NM_001127582.1) - CDCR348732 from Creative Biomart Species Human Accession NM_001127582.1

Human ING4 ORF Clone(NM_001127583.1) - CDCR348733 from Creative Biomart Species Human Accession NM_001127583.1

Human ING4 ORF Clone(NM_001127583.1) - CDCR348734 from Creative Biomart Species Human Accession NM_001127583.1

Human ING4 ORF Clone(NM_001127584.1) - CDCR348735 from Creative Biomart Species Human Accession NM_001127584.1

Human ING4 ORF Clone(NM_001127582.1) - CDCR348736 from Creative Biomart Species Human Accession NM_001127582.1

Human ING4 ORF Clone(NM_001127584.1) - CDCR348737 from Creative Biomart Species Human Accession NM_001127584.1

Human ING4 ORF Clone(NM_001127585.1) - CDCR348738 from Creative Biomart Species Human Accession NM_001127585.1

Human ING4 ORF Clone(NM_001127586.1) - CDCR348739 from Creative Biomart Species Human Accession NM_001127586.1

Human ING4 ORF Clone(NM_001127586.1) - CDCR348740 from Creative Biomart Species Human Accession NM_001127586.1

Human ING4 ORF Clone(NM_001127585.1) - CDCR348742 from Creative Biomart Species Human Accession NM_001127585.1

Human ING4 Gene ORF cDNA clone in cloning vector - HG14264-G from Sino Biological Species Human

Human ING4 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14264-NF from Sino Biological Species Human

Human ING4 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14264-NM from Sino Biological Species Human

Human ING4 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14264-CF from Sino Biological Species Human

Human ING4 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14264-CM from Sino Biological Species Human

Human ING4 Gene ORF cDNA clone expression plasmid, N-His tag - HG14264-NH from Sino Biological Species Human

Human ING4 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14264-ANG from Sino Biological Species Human

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